Factors affecting the relationship between psychological status and quality of life in COPD patients

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  • dc.contributor.author Balcells Vilarnau, Eva, 1967-ca
  • dc.contributor.author Gea Guiral, Joaquimca
  • dc.contributor.author Ferrer, Jaumeca
  • dc.contributor.author Serra, Ignasica
  • dc.contributor.author Orozco Levi, Mauricioca
  • dc.contributor.author Batlle Garcia, Jordi de, 1981-ca
  • dc.contributor.author Rodríguez, Estherca
  • dc.contributor.author Benet, Martaca
  • dc.contributor.author Donaire González, Davidca
  • dc.contributor.author Antó i Boqué, Josep Mariaca
  • dc.contributor.author García Aymerich, Judithca
  • dc.contributor.author PAC-COPD Study Groupca
  • dc.date.accessioned 2015-06-12T07:37:36Z
  • dc.date.available 2015-06-12T07:37:36Z
  • dc.date.issued 2010ca
  • dc.description.abstract Background: This study aims to (i) evaluate the association between anxiety and depressive symptoms and health-related quality of life (HRQoL); and (ii) identify the effect modifiers of this relationship in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 337 clinically stable COPD patients answered the St. George's Respiratory Questionnaire (SGRQ) (assessing HRQoL) and the Hospital Anxiety and Depression Scale (HADS). Socio-demographic information, lung function, and other clinical data were collected. Results: Most patients (93%) were male; they had a mean (SD) age of 68 (9) years and mild to very severe COPD (post-bronchodilator FEV1 52 (16)% predicted). Multivariate analyses showed that anxiety, depression, or both conditions were associated with poor HRQoL (for all SGRQ domains). The association between anxiety and total HRQoL score was 6.7 points higher (indicating a worse HRQoL) in current workers than in retired individuals. Estimates for patients with "both anxiety and depression" were 5.8 points lower in stage I-II than in stage III-IV COPD, and 10.2 points higher in patients with other comorbidities than in those with only COPD. Conclusions: This study shows a significant association between anxiety, depression, or both conditions and impaired HRQoL. Clinically relevant factors affecting the magnitude of this association include work status, COPD severity, and the presence of comorbidities.en
  • dc.description.sponsorship This study was supported by grants from Fondo de Investigación Sanitaria (FIS PI020541), Ministry of Health, Spain; Agència d'Avaluació de Tecnologia i Recerca Mèdiques (AATRM 035/20/02), Catalonia Government; Spanish Society of Pneumology and Thoracic Surgery (SEPAR 2002/137); Catalan Foundation of Pneumology (FUCAP 2003 Beca Marià Ravà); Red RESPIRA (RTIC C03/11); Red RCESP (RTIC C03/09), Fondo de Investigación Sanitaria (PI052486); Fondo de Investigación Sanitaria (PI052302); Fundació La Marató de TV3 (num. 041110); DURSI (2005SGR00392); Novartis Farmacèutica, Spain. CIBERESP and CIBERES are funded by the Instituto de Salud Carlos III, Ministry of Health, Spain. Judith Garcia-Aymerich has a researcher contract from the Instituto de Salud Carlos III (CP05/00118), Ministry of Health, Spain.en
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Balcells E, Gea J, Ferrer J, Serra I, Orozco-Levi M, de Batlle J et al. Factors affecting the relationship between psychological status and quality of life in COPD patients. Health and quality of life outcomes. 2010;8:108. DOI: 10.1186/1477-7525-8-108ca
  • dc.identifier.doi http://dx.doi.org/10.1186/1477-7525-8-108
  • dc.identifier.issn 1477-7525ca
  • dc.identifier.uri http://hdl.handle.net/10230/23796
  • dc.language.iso engca
  • dc.publisher BioMed Centralca
  • dc.relation.ispartof Health and quality of life outcomes. 2010;8:108
  • dc.rights © 2010 Balcells et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri http://creativecommons.org/licenses/by/2.0
  • dc.subject.other Pulmons -- Malalties obstructivesca
  • dc.subject.other Pulmons -- Malalties -- Estudi de casosca
  • dc.title Factors affecting the relationship between psychological status and quality of life in COPD patientsen
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca

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Articles (Departament de Medicina i Ciències de la Vida)
Articles (Barcelona Institute for Global Health (ISGlobal) – Campus Mar)