A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1
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- dc.contributor.author Fraile Beneitez, Rodrigo
- dc.contributor.author Sánchez Mir, Laura
- dc.contributor.author Hidalgo Hernando, Elena
- dc.date.accessioned 2019-12-03T10:15:48Z
- dc.date.issued 2020
- dc.description.abstract Survival upon glucose starvation requires a delicate balance between different metabolic pathways. A recent work by the Roe laboratory provides a mechanistic link between glucose deprivation and the regulation of the pentose phosphate pathway, with the transcriptional repressor Rsv1 playing a key role in the process. Rsv1 regulates the flow of glucose into its possible metabolic fates and promotes long-term survival under low glucose.
- dc.description.sponsorship This work is supported by the Ministerio de Ciencia, Innovación y Universidades (Spain), PLAN E, and FEDER (PGC2018-093920-B-I00) to EH. The Oxida-tive Stress and Cell Cycle group is also supported by Generalitat de Catalunya (Spain) (2017-SGR-539) and by Unidad de Excelencia María de Maeztu from MINECO (Spain) (MDM-2014-0370). EH is recipientof an ICREA Academia Award (Generalitat de Catalunya, Spain)
- dc.format.mimetype application/pdf
- dc.identifier.citation Fraile R, Sánchez-Mir L, Hidalgo E. A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1. FEBS J. 2020;287(5):874-7. DOI: 10.1111/febs.15131
- dc.identifier.doi http://dx.doi.org/10.1111/febs.15131
- dc.identifier.issn 1742-464X
- dc.identifier.uri http://hdl.handle.net/10230/43063
- dc.language.iso eng
- dc.publisher Wiley-VCH Verlag
- dc.relation.ispartof FEBS J. 2020;287(5):874-7
- dc.rights © 2019 Federation of European Biochemical Societies. A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1. Rodrigo Fraile, Laura Sanchez-Mir, Elena Hidalgo. FEBS Journal, vol. 287, núm. 5
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.other Schizosaccharomyces pombe
- dc.subject.other Glucosa
- dc.title A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion