A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1

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dc.contributor.authorFraile Beneitez, Rodrigo
dc.contributor.authorSánchez Mir, Laura
dc.contributor.authorHidalgo Hernando, Elena
dc.date.accessioned2019-12-03T10:15:48Z
dc.date.issued2020
dc.description.abstractSurvival upon glucose starvation requires a delicate balance between different metabolic pathways. A recent work by the Roe laboratory provides a mechanistic link between glucose deprivation and the regulation of the pentose phosphate pathway, with the transcriptional repressor Rsv1 playing a key role in the process. Rsv1 regulates the flow of glucose into its possible metabolic fates and promotes long-term survival under low glucose.
dc.description.sponsorshipThis work is supported by the Ministerio de Ciencia, Innovación y Universidades (Spain), PLAN E, and FEDER (PGC2018-093920-B-I00) to EH. The Oxida-tive Stress and Cell Cycle group is also supported by Generalitat de Catalunya (Spain) (2017-SGR-539) and by Unidad de Excelencia María de Maeztu from MINECO (Spain) (MDM-2014-0370). EH is recipientof an ICREA Academia Award (Generalitat de Catalunya, Spain)
dc.format.mimetypeapplication/pdf
dc.identifier.citationFraile R, Sánchez-Mir L, Hidalgo E. A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1. FEBS J. 2020;287(5):874-7. DOI: 10.1111/febs.15131
dc.identifier.doihttp://dx.doi.org/10.1111/febs.15131
dc.identifier.issn1742-464X
dc.identifier.urihttp://hdl.handle.net/10230/43063
dc.language.isoeng
dc.publisherWiley-VCH Verlag
dc.relation.ispartofFEBS J. 2020;287(5):874-7
dc.rights© 2019 Federation of European Biochemical Societies. A new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1. Rodrigo Fraile, Laura Sanchez-Mir, Elena Hidalgo. FEBS Journal, vol. 287, núm. 5
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.subject.otherSchizosaccharomyces pombe
dc.subject.otherGlucosa
dc.titleA new adaptation strategy to glucose starvation: modulation of the gluconate shunt and pentose phosphate pathway by the transcriptional repressor Rsv1
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion

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