Mean bone material strength index values for women are lower than those for men: Data from a single geographical location
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- dc.contributor.author Holloway-Kew, Kara L.
- dc.contributor.author Rufus-Membere, Pamela
- dc.contributor.author Anderson, Kara B.
- dc.contributor.author Harland, Jacob W.
- dc.contributor.author Diez-Perez, Adolfo
- dc.contributor.author Kotowicz, Mark A.
- dc.contributor.author Pasco, Julie A.
- dc.date.accessioned 2024-04-26T06:32:43Z
- dc.date.available 2024-04-26T06:32:43Z
- dc.date.issued 2023
- dc.description.abstract Bone material strength index (BMSi) values are obtained using impact microindentation, which assesses the ability of bone to resist indentation. Differences in BMSi between men and women are unclear, and to date, BMSi sex differences have not been compared for individuals from the same population. Therefore, we compared BMSi values for men and women drawn from the same geographical location in Australia. Participants (n = 220) were from the Geelong Osteoporosis Study. BMSi was measured, following international published guidelines, using an OsteoProbe for participants at recent follow-up phases (women 2022-2023 and men 2016-2022). Women (n = 55) were age matched to men (n = 165) in a 1:3 ratio. A two-sample t test was used to determine the intergroup difference in mean BMSi. Linear regression was also performed, adjusting for weight and height. Median (IQR) ages for men and women were 67.0 (61.7-71.5) and 67.4 (62.0-71.2) years (p = 0.998). Men were heavier (81.0 ± 10.9 vs 71.0 ± 13.9 kg, p < 0.001) and taller (173.9 ± 6.4 vs 161.5 ± 7.5 cm, p < 0.001) than women. Mean (± SD) BMSi for women (75.7 ± 7.4) was lower than for men (82.8 ± 6.8) (p < 0.001). The difference persisted after adjustment for weight and height (mean ± SE: 76.5 ± 1.1 vs 82.5 ± 0.6, p < 0.001). Given the higher fracture risk observed for women, the higher mean BMSi values in men are consistent with cross sectional data suggesting this measure may be useful in fracture prediction.
- dc.format.mimetype application/pdf
- dc.identifier.citation Holloway-Kew KL, Rufus-Membere PG, Anderson KB, Harland JW, Diez-Perez A, Kotowicz MA, et al. Mean bone material strength index values for women are lower than those for men: Data from a single geographical location. Calcif Tissue Int. 2023 Nov;113(5):511-4. DOI: 10.1007/s00223-023-01133-9
- dc.identifier.doi http://dx.doi.org/10.1007/s00223-023-01133-9
- dc.identifier.issn 0171-967X
- dc.identifier.uri http://hdl.handle.net/10230/59911
- dc.language.iso eng
- dc.publisher Springer
- dc.relation.ispartof Calcif Tissue Int. 2023 Nov;113(5):511-4
- dc.rights © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Bone material strength index
- dc.subject.keyword Impact microindentation
- dc.subject.keyword Men
- dc.subject.keyword Women
- dc.title Mean bone material strength index values for women are lower than those for men: Data from a single geographical location
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion