The Genomic Footprints of the Fall and Recovery of the Crested Ibis

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• dc.contributor.author Feng, Shaohong
• dc.contributor.author Fang, Qi
• dc.contributor.author Barnett, Ross
• dc.contributor.author Li, Cai
• dc.contributor.author Han, Sojung
• dc.contributor.author Kuhlwilm, Martin
• dc.contributor.author Zhou, Long
• dc.contributor.author Pan, Hailin
• dc.contributor.author Deng, Yuan
• dc.contributor.author Chen, Guangji
• dc.contributor.author Gamauf, Anita
• dc.contributor.author Woog, Friederike
• dc.contributor.author Prys-Jones, Robert
• dc.contributor.author Marquès i Bonet, Tomàs, 1975-
• dc.contributor.author Gilbert, M Thomas
• dc.contributor.author Zhang, Guojie
• dc.date.accessioned 2019-03-05T08:14:33Z
• dc.date.available 2019-03-05T08:14:33Z
• dc.date.issued 2019
• dc.description.abstract Human-induced environmental change and habitat fragmentation pose major threats to biodiversity and require active conservation efforts to mitigate their consequences. Genetic rescue through translocation and the introduction of variation into imperiled populations has been argued as a powerful means to preserve, or even increase, the genetic diversity and evolutionary potential of endangered species [1-4]. However, factors such as outbreeding depression [5, 6] and a reduction in available genetic diversity render the success of such approaches uncertain. An improved evaluation of the consequence of genetic restoration requires knowledge of temporal changes to genetic diversity before and after the advent of management programs. To provide such information, a growing number of studies have included small numbers of genomic loci extracted from historic and even ancient specimens [7, 8]. We extend this approach to its natural conclusion, by characterizing the complete genomic sequences of modern and historic population samples of the crested ibis (Nipponia nippon), an endangered bird that is perhaps the most successful example of how conservation effort has brought a species back from the brink of extinction. Though its once tiny population has today recovered to >2,000 individuals [9], this process was accompanied by almost half of ancestral loss of genetic variation and high deleterious mutation load. We furthermore show how genetic drift coupled to inbreeding following the population bottleneck has largely purged the ancient polymorphisms from the current population. In conclusion, we demonstrate the unique promise of exploiting genomic information held within museum samples for conservation and ecological research.
• dc.description.sponsorship This work was supported by the Strategic Priority Research Program of Chinese Academy of Sciences (XDB31020000, XDB13000000), Carlsberg Foundation grant to G.Z. (CF16-0663), ERC Consolidator Grant 681396 ‘Extinction Genomics’ (M.T.P.G.), BFU2017-86471-P (MINECO/FEDER, UE) (T.M.-B.), U01 MH106874 grant (T.M.-B.), Howard Hughes International Early Career (T.M.-B.), Obra Social “La Caixa” and Secretaria d’Universitats i Recerca (T.M.-B.), CERCA Programme del Departament d’Economia i Coneixement de la Generalitat de Catalunya (T.M.-B.), and Deutsche Forschungsgemeinschaft (DFG) fellowship (KU 3467/1-1) (M.K.).
• dc.format.mimetype application/pdf
• dc.identifier.citation Feng S, Fang Q, Barnett R, Li C, Han S, Kuhlwilm M et al. The Genomic Footprints of the Fall and Recovery of the Crested Ibis. Curr Biol. 2019;29(2):340-9. DOI: 10.1016/j.cub.2018.12.008
• dc.identifier.doi http://dx.doi.org/10.1016/j.cub.2018.12.008
• dc.identifier.issn 0960-9822
• dc.identifier.uri http://hdl.handle.net/10230/36731
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Current Biology. 2019;29(2):340-9
• dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/681396
• dc.rights © 2018 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
• dc.subject.keyword Conservation genomics
• dc.subject.keyword Population genomics
• dc.subject.keyword Endangered species
• dc.subject.keyword Extinction
• dc.subject.keyword Demography
• dc.subject.keyword Inbreeding
• dc.subject.keyword Mutation load
• dc.subject.keyword Genetic recovery
• dc.subject.keyword Ancient genomics
• dc.subject.keyword Ornithology
• dc.title The Genomic Footprints of the Fall and Recovery of the Crested Ibis
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion