Left atrium assessment by speckle tracking echocardiography in cryptogenic stroke: seeking silent atrial fibrillation

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  • dc.contributor.author Ble, Mireia
  • dc.contributor.author Benito Villabriga, Begoña
  • dc.contributor.author Cuadrado-Godia, Elisa
  • dc.contributor.author Pérez-Fernández, Silvia
  • dc.contributor.author Gómez Pérez, Miguel Angel
  • dc.contributor.author Mas Stachurska, Aleksandra
  • dc.contributor.author Tizón-Marcos, Helena
  • dc.contributor.author Molina Ferragut, Luis
  • dc.contributor.author Martí-Almor, Julio
  • dc.contributor.author Cladellas Capdevila, M.Mercedes
  • dc.date.accessioned 2022-06-21T06:49:11Z
  • dc.date.available 2022-06-21T06:49:11Z
  • dc.date.issued 2021
  • dc.description.abstract Silent atrial fibrillation (AF) may be the cause of some cryptogenic strokes (CrS). The aim of the study was to analyse atrial size and function by speckle tracking echocardiography in CrS patients to detect atrial disease. Patients admitted to the hospital due to CrS were included prospectively. Echocardiogram analysis included left atrial ejection fraction (LAEF) and atrial strain. Insertable cardiac monitor was implanted, and AF was defined as an episode of ≥1 min in the first year after stroke. Left atrial enlargement was defined as indexed volume > 34 mL/m2. Seventy-five consecutive patients were included, aged 76 ± 9 years (arterial hypertension 75%). AF was diagnosed in 49% of cases. The AF group had higher atrial volume and worse atrial function: peak atrial longitudinal strain (PALs) 19.6 ± 5.7% vs. 29.5 ± 7.2%, peak atrial contraction strain (PACs) 8.9 ± 3.9% vs. 16.5 ± 6%, LAEF 46.8 ± 11.5% vs. 60.6 ± 5.2%; p < 0.001. AF was diagnosed in 20 of 53 patients with non-enlarged atrium, and in 18 of them, atrial dysfunction was present. The multivariate logistic regression analysis demonstrated an independent association between detection of AF and atrial volume, LAEF, and strain. Cut-off values were obtained: LAEF < 55%, PALs < 21.4%, and PACs < 12.9%. In conclusion, speckle tracking echocardiography in CrS patients improves silent atrial disease diagnosis, with or without atrial enlargement.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Ble M, Benito B, Cuadrado-Godia E, Pérez-Fernández S, Gómez M, Mas-Stachurska A, et al. Left atrium assessment by speckle tracking echocardiography in cryptogenic stroke: seeking silent atrial fibrillation. J Clin Med. 2021 Aug 9; 10(16): 3501. DOI: 10.3390/jcm10163501
  • dc.identifier.doi http://dx.doi.org/10.3390/jcm10163501
  • dc.identifier.issn 2077-0383
  • dc.identifier.uri http://hdl.handle.net/10230/53551
  • dc.language.iso eng
  • dc.publisher MDPI
  • dc.rights Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword Atrial disease
  • dc.subject.keyword Atrial fibrillation
  • dc.subject.keyword Atrial strain
  • dc.subject.keyword Cryptogenic stroke
  • dc.subject.keyword Echocardiography
  • dc.title Left atrium assessment by speckle tracking echocardiography in cryptogenic stroke: seeking silent atrial fibrillation
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion