A high throughput genotyping approach reveals distinctive autosomal genetic signatures for European and near Eastern wild boar

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• dc.contributor.author Manunza, Arianna
• dc.contributor.author Zidi, Ali
• dc.contributor.author Yeghoyan, Seryozha
• dc.contributor.author Balteanu, Valentin Adrian
• dc.contributor.author Carsai, Teodora Crina
• dc.contributor.author Scherbakov, Oleg
• dc.contributor.author Ramírez, Oscar
• dc.contributor.author Eghbalsaied, Shahin
• dc.contributor.author Castelló, Anna
• dc.contributor.author Mercadé, Anna
• dc.contributor.author Amills, Marcel
• dc.date.accessioned 2024-01-16T06:55:12Z
• dc.date.available 2024-01-16T06:55:12Z
• dc.date.issued 2013
• dc.description.abstract The lack of a Near Eastern genetic signature in modern European porcine breeds indicates that, although domestic pigs from the Fertile Crescent entered Europe during the Neolithic, they were completely replaced by their European counterparts in a short window of time. Whilst the absence of such genetic signature has been convincingly demonstrated at the mitochondrial level, variation at the autosomal genomes of European and Near Eastern Sus scrofa has not been compared yet. Herewith, we have explored the genetic relationships among 43 wild boar from Europe (N = 21), Near East (N = 19) and Korea (N = 3), and 40 Iberian (N = 16), Canarian (N = 4) and Mangalitza (N = 20) pigs by using a high throughput SNP genotyping platform. After data filtering, 37,167 autosomal SNPs were used to perform population genetics analyses. A multidimensional scaling plot based on genome-wide identity-by-state pairwise distances inferred with PLINK showed that Near Eastern and European wild boar populations are genetically differentiated. Maximum likelihood trees built with TreeMix supported this conclusion i.e. an early population split between Near Eastern and European Sus scrofa was observed. Moreover, analysis of the data with Structure evidenced that the sampled Iberian, Canarian and Mangalitza pigs did not carry any autosomal signature compatible with a Near Eastern ancestry, a finding that agrees well with previous mitochondrial studies.
• dc.description.sponsorship This work has been funded by grants AGL2010-22208-C02-02 (Ministerio de Ciencia e Innovación) and CSD 2007-00036 (Ministerio de Ciencia e Innovación, Consolider Ingenio 2010 Program). A. Zidi received a contractual grant under the framework of CSD 2007-00036. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
• dc.format.mimetype application/pdf
• dc.identifier.citation Manunza A, Zidi A, Yeghoyan S, Balteanu VA, Carsai TC, Scherbakov O, et al. A high throughput genotyping approach reveals distinctive autosomal genetic signatures for European and near Eastern wild boar. PLoS ONE. 2013 Feb 27;8(2):e55891. DOI: 10.1371/journal.pone.0055891
• dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0055891
• dc.identifier.issn 1932-6203
• dc.identifier.uri http://hdl.handle.net/10230/58703
• dc.language.iso eng
• dc.publisher Public Library of Science (PLoS)
• dc.relation.projectID info:eu-repo/grantAgreement/ES/PN/CSD2007-00036
• dc.relation.projectID info:eu-repo/grantAgreement//ES/3PN/AGL2010-22208-C02-02
• dc.rights © 2013 Manunza et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.other Mitocondris
• dc.subject.other Senglar
• dc.subject.other Genomes
• dc.title A high throughput genotyping approach reveals distinctive autosomal genetic signatures for European and near Eastern wild boar
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion