Reconstructing the Indian origin and dispersal of the european Roma: a maternal genetic perspective
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Mendizábal Eceizabarrena, Isabel, 1981-ca
- dc.contributor.author Valente, Cristinaca
- dc.contributor.author Gusmao, Alfredoca
- dc.contributor.author Alves, Cíntiaca
- dc.contributor.author Gomes, Verónicaca
- dc.contributor.author Goios, Anaca
- dc.contributor.author Parson, Waltherca
- dc.contributor.author Calafell i Majó, Francescca
- dc.contributor.author Alvarez, Luisca
- dc.contributor.author Amorim, Antónioca
- dc.contributor.author Gusmao, Leonorca
- dc.contributor.author Comas, David, 1969-ca
- dc.contributor.author Prata, Maria Joaoca
- dc.date.accessioned 2015-04-29T09:17:15Z
- dc.date.available 2015-04-29T09:17:15Z
- dc.date.issued 2011ca
- dc.description.abstract Previous genetic, anthropological and linguistic studies have shown that Roma (Gypsies) constitute a founder population dispersed throughout Europe whose origins might be traced to the Indian subcontinent. Linguistic and anthropological evidence point to Indo-Aryan ethnic groups from North-western India as the ancestral parental population of Roma. Recently, a strong genetic hint supporting this theory came from a study of a private mutation causing primary congenital glaucoma. In the present study, complete mitochondrial control sequences of Iberian Roma and previously published maternal lineages of other European Roma were analyzed in order to establish the genetic affinities among Roma groups, determine the degree of admixture with neighbouring populations, infer the migration routes followed since the first arrival to Europe, and survey the origin of Roma within the Indian subcontinent. Our results show that the maternal lineage composition in the Roma groups follows a pattern of different migration routes, with several founder effects, and low effective population sizes along their dispersal. Our data allowed the confirmation of a North/West migration route shared by Polish, Lithuanian and Iberian Roma. Additionally, eleven Roma founder lineages were identified and degrees of admixture with host populations were estimated. Finally, the comparison with an extensive database of Indian sequences allowed us to identify the Punjab state, in North-western India, as the putative ancestral homeland of the European Roma, in agreement with previous linguistic and anthropological studies.en
- dc.description.sponsorship IM was supported by a fellowship by the Basque Government (Hezkuntza, Unibertsitate eta Ikerketa Saila, Eusko Jaurlaritza, BFI107.4). Fundaçao para a Ciencia e Tecnologia (FCT) supported CV, VG, AG and LA through grants SFRH/BD/63343/2009, SFRH/BD/36045/2007, SFRH/BPD/43646/2008 and SFRH/BPD/65000/2009, respectively. This work was partially financed by FCT through project PTDC/AN /70413/2006 and POCI 2010, Programa Operacional Ciencia e Inovaçao; Dirección General de Investigación, Ministerio de Educación y Ciencia, Spain (CGL2009-14944/BOS); Direcció General de Recerca, Generalitat de Catalunya (2009SGR1101) and the Austrian Science Fund (FWF): TR397. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscripten
- dc.format.mimetype application/pdfca
- dc.identifier.citation Mendizabal I, Valente C, Gusmao A, Alves C, Gomes V, Goios A et al. Reconstructing the Indian origin and dispersal of the european Roma: a maternal genetic perspective. PLoS ONE. 2011;6(1):e15988. DOI: 10.1371/journal.pone.0015988ca
- dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0015988
- dc.identifier.issn 1932-6203ca
- dc.identifier.uri http://hdl.handle.net/10230/23493
- dc.language.iso engca
- dc.publisher Public Library of Science (PLoS)ca
- dc.relation.ispartof PLoS ONE. 2011;6(1):e15988
- dc.rights © 2011 Mendizabal et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are crediteden
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.subject.other ADN mitocondrialca
- dc.subject.other Genètica de poblacions humanesca
- dc.subject.other Glaucomaca
- dc.title Reconstructing the Indian origin and dispersal of the european Roma: a maternal genetic perspectiveen
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersionca