Status quo of pain-related patient-reported outcomes and perioperative pain management in 10,415 patients from 10 countries: Analysis of registry data

PAIN OUT Research Group Jena; Chinese PAIN OUT network; Dutch PAIN OUT network; Méxican PAIN OUT network; Serbian PAIN OUT network; Spanish PAIN OUT network; French PAIN OUT network; Italian PAIN OUT network; Swiss PAIN OUT network; Irish PAIN OUT network; Belgian PAIN OUT network; Zaslansky, Ruth

Status quo of pain-related patient-reported outcomes and perioperative pain management in 10,415 patients from 10 countries: Analysis of registry data

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dc.contributor.author PAIN OUT Research Group Jena
dc.contributor.author Chinese PAIN OUT network
dc.contributor.author Dutch PAIN OUT network
dc.contributor.author Méxican PAIN OUT network
dc.contributor.author Serbian PAIN OUT network
dc.contributor.author Spanish PAIN OUT network
dc.contributor.author French PAIN OUT network
dc.contributor.author Italian PAIN OUT network
dc.contributor.author Swiss PAIN OUT network
dc.contributor.author Irish PAIN OUT network
dc.contributor.author Belgian PAIN OUT network
dc.contributor.author Zaslansky, Ruth
dc.date.accessioned 2024-05-06T05:46:12Z
dc.date.available 2024-05-06T05:46:12Z
dc.date.issued 2022
dc.description.abstract Background: Postoperative pain is common at the global level, despite considerable attempts for improvement, reflecting the complexity of offering effective pain relief. In this study, clinicians from Mexico, China, and eight European countries evaluated perioperative pain practices and patient-reported outcomes (PROs) in their hospitals as a basis for carrying out quality improvement (QI) projects in each country. Methods: PAIN OUT, an international perioperative pain registry, provided standardized methodology for assessing management and multi-dimensional PROs on the first postoperative day, in patients undergoing orthopaedic, general surgery, obstetric & gynaecology or urological procedures. Results: Between 2017 and 2019, data obtained from 10,415 adult patients in 105 wards, qualified for analysis. At the ward level: 50% (median) of patients reported worst pain intensities ≥7/10 NRS, 25% spent ≥50% of the time in severe pain and 20-34% reported severe ratings for pain-related functional and emotional interference. Demographic variables, country and surgical discipline explained a small proportion of the variation in the PROs, leaving about 88% unexplained. Most treatment processes varied considerably between wards. Ward effects accounted for about 7% and 32% of variation in PROs and treatment processes, respectively. Conclusions: This comprehensive evaluation demonstrates that many patients in this international cohort reported poor pain-related PROs on the first postoperative day. PROs and treatments varied greatly. Most of the variance of the PROs could not be explained. The findings served as a basis for devising and implementing QI programmes in participating hospitals. Significance: In preparation for quality improvement projects, we comprehensively evaluated pain-related patient-reported outcomes (PROs) and treatment practices of 10,415 adult patients spanning 10 countries. PROs were generally poor. Demographics, country and surgical discipline explained a small proportion of variation for the PROs, about 88% remained unexplained. Treatment practices varied considerably between wards. Ward effects accounted for about 7% and 32% of variation in PROs and treatment processes, respectively. Future studies will aim to identify treatments which are associated with improved outcomes.
dc.description.sponsorship [i] European Community’s Seventh Framework Programme FP7/2007–2013 under Grant Agreement No. 223590; [ii] Unrestricted educational grants for quality improvement studies from Pfizer Global Medical Grants (Mexico and China); [iii] European Pain Federation (EFIC) and Grünenthal GmbH within their CHANGE PAIN® acute initiative (Belgium, Italy, Ireland, France, The Netherlands, Spain, Switzerland); [iv] EFIC (Serbia).
dc.format.mimetype application/pdf
dc.identifier.citation PAIN OUT Research Group Jena; Chinese PAIN OUT network; Dutch PAIN OUT network; Méxican PAIN OUT network; Serbian PAIN OUT network; Spanish PAIN OUT network, et al. Status quo of pain-related patient-reported outcomes and perioperative pain management in 10,415 patients from 10 countries: Analysis of registry data. Eur J Pain. 2022 Nov;26(10):2120-40. DOI: 10.1002/ejp.2024
dc.identifier.doi http://dx.doi.org/10.1002/ejp.2024
dc.identifier.issn 1090-3801
dc.identifier.uri http://hdl.handle.net/10230/60020
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartof Eur J Pain. 2022 Nov;26(10):2120-40
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/223590
dc.rights © 2022 The Authors. European Journal of Pain published by John Wiley & Sons Ltd on behalf of European Pain Federation - EFIC ®. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.other Postoperatori
dc.title Status quo of pain-related patient-reported outcomes and perioperative pain management in 10,415 patients from 10 countries: Analysis of registry data
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/publishedVersion

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