Influenza vaccination coverage rates and determinants in Greek children until the age of ten (2008-2019), the Rhea mother-child cohort
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- dc.contributor.author Karachaliou, Marianna
- dc.contributor.author Damianaki, Irene
- dc.contributor.author Moudatsaki, Maria
- dc.contributor.author Margetaki, Katerina
- dc.contributor.author Roumeliotaki, Theano
- dc.contributor.author Bempi, Vicky
- dc.contributor.author Moudatsaki, Marina
- dc.contributor.author Chatzi, Lida Vaia
- dc.contributor.author Vafeiadi, Marina, 1983-
- dc.contributor.author Kogevinas, Manolis
- dc.date.accessioned 2023-11-28T07:12:53Z
- dc.date.available 2023-11-28T07:12:53Z
- dc.date.issued 2023
- dc.description.abstract Background: In Greece, influenza vaccination is currently recommended for children with high-risk conditions. There are limited data on influenza vaccination uptake among Greek children with and without high-risk conditions. We aim to describe the annual influenza vaccination uptake until the age of ten in a population-based mother-child cohort and identify the factors influencing vaccination rates. Methods: Immunization data from the child's health cards at 4 and 10 years were available for 830 and 298 children participating in the Rhea cohort (2008-2019). We calculated vaccination coverage by age, winter season and among children with asthma and obesity for whom the vaccine is indicated. Univariable and multivariable stepwise logistic regression models were utilized to identify the association between several sociodemographic, lifestyle and health-related variables and vaccine uptake by age four. Results: By the ages of four and ten, 37% and 40% of the children, respectively, had received at least one influenza vaccination. Only 2% of the children were vaccinated for all winter seasons during their first four years of life. The vaccination rate was highest at the age of two and during the 2009-2010 season. Vaccination rates for children with asthma and obesity were 18.2% and 13.3% at age four and 8.3% and 2.9% at age ten. About 10% of all vaccines were administered after December and 24% of the children received only one dose upon initial vaccination. Children with younger siblings and those who had experienced more respiratory infections were more likely to be vaccinated by the age of four, while children exposed to smoking were less likely to be vaccinated. Conclusions: Children in our study were more likely to be vaccinated against influenza at an early age with the peak occurring at the age of two. Nonetheless, annual vaccination uptake was uncommon. Vaccination rates of children with asthma and obesity were well below the national target of 75% for individuals with chronic conditions. Certain groups may merit increased attention in future vaccination campaigns such as children raised in families with unfavourable health behaviours.
- dc.description.sponsorship This work was supported by the Greek Ministry of Health (program of prevention of obesity and neurodevelopmental disorders in preschool children, in the Heraklion district, Crete, Greece, 2011–2014; and “Rhea Plus”: Primary Prevention Program of Environmental Risk Factors for Reproductive Health and Child Health, 2012–2015). We acknowledge support from the grant CEX2018-000806-S funded by MCIN/AEI/10.13039/501100011033, and support from the Generalitat de Catalunya through the CERCA Program. The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or the decision to submit the manuscript for publication.
- dc.format.mimetype application/pdf
- dc.identifier.citation Karachaliou M, Damianaki I, Moudatsaki M, Margetaki K, Roumeliotaki T, Bempi V, Moudatsaki M, Chatzi LV, Vafeiadi M, Kogevinas M. Influenza vaccination coverage rates and determinants in Greek children until the age of ten (2008-2019), the Rhea mother-child cohort. Vaccines (Basel). 2023 Jul 14;11(7):1241. DOI: 10.3390/vaccines11071241
- dc.identifier.doi http://dx.doi.org/10.3390/vaccines11071241
- dc.identifier.issn 2076-393X
- dc.identifier.uri http://hdl.handle.net/10230/58407
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof Vaccines (Basel). 2023 Jul 14;11(7):1241
- dc.relation.projectID info:eu-repo/grantAgreement/ES/2PE/CEX2018-000806-S
- dc.rights © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Greece
- dc.subject.keyword Asthma
- dc.subject.keyword Children
- dc.subject.keyword Influenza
- dc.subject.keyword Obesity
- dc.subject.keyword Vaccine
- dc.title Influenza vaccination coverage rates and determinants in Greek children until the age of ten (2008-2019), the Rhea mother-child cohort
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion