Health-related quality of life in long-term colorectal cancer survivors
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- dc.contributor.author Marcos-Delgado, Alba
- dc.contributor.author Martín Sánchez, Vicente
- dc.contributor.author Molina-Barceló, Ana
- dc.contributor.author Alonso-Molero, Jéssica
- dc.contributor.author Pérez-Gómez, Beatriz
- dc.contributor.author Pollán, Marina
- dc.contributor.author Aragonés, Núria
- dc.contributor.author Ederra, María
- dc.contributor.author Fernández-Tardón, Guillermo
- dc.contributor.author Binefa, Gemma
- dc.contributor.author Moreno, Víctor
- dc.contributor.author Barrios-Rodríguez, Rocío
- dc.contributor.author Amiano, Pilar
- dc.contributor.author Huerta, José María
- dc.contributor.author Pastor Teso, Enrique
- dc.contributor.author Alguacil Ojeda, Juan
- dc.contributor.author Castaño Vinyals, Gemma
- dc.contributor.author Kogevinas, Manolis
- dc.contributor.author Molina de la Torre, Antonio José
- dc.date.accessioned 2024-11-27T07:02:29Z
- dc.date.available 2024-11-27T07:02:29Z
- dc.date.issued 2024
- dc.description.abstract The aim of our study is to evaluate the relationship between sociodemographic and clinical characteristics of individuals with Colorectal Cancer (CRC), tumour-intrinsic characteristics and treatment received with health-related quality of life (HRQoL). Methods: Cross-sectional analysis of data from 805 survivors from the MCC study was conducted. HRQoL was assessed through a general and specific questionnaire, SF-12 and FCSI (Colorectal Symptom Index). Statistical analyses were performed with linear regression with adjustment for sociodemographic variables, stage at diagnosis and histological grade. Results: Participants had survived a median of 7.9 years from diagnosis (IQR 7.1-8.5 years). Age at diagnosis, sex and area showed a clear association with HRQoL in both physical and mental dimensions of the SF-12 questionnaire. A direct association between CRC recurrence was also found in the PCS-12 and MCS-12 dimensions and radical surgery in the PCS-12. Regarding the scores in FCSI questionnaire, statistically significant differences were observed by sex, age and area, with older women being the most impaired (p < 0.001). Conclusions: Age, sex and area was associated with lower scores of HRQoL among CRC survivors. Knowing the determinants related to HRQoL would allow us to lay the groundwork to develop strategies that help reduce morbidity and mortality, relapses and increase HRQoL.
- dc.format.mimetype application/pdf
- dc.identifier.citation Marcos-Delgado A, Martín-Sánchez V, Molina-Barceló A, Alonso-Molero J, Pérez-Gómez B, Pollán M, et al. Health-related quality of life in long-term colorectal cancer survivors. Healthcare (Basel). 2024 Sep 25;12(19):1917. DOI: 10.3390/healthcare12191917
- dc.identifier.doi http://dx.doi.org/10.3390/healthcare12191917
- dc.identifier.issn 2227-9032
- dc.identifier.uri http://hdl.handle.net/10230/68832
- dc.language.iso eng
- dc.publisher MDPI
- dc.relation.ispartof Healthcare (Basel). 2024 Sep 25;12(19):1917
- dc.rights © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Cancer survivors
- dc.subject.keyword Colorectal cancer
- dc.subject.keyword Health-related quality of life (HRQoL)
- dc.title Health-related quality of life in long-term colorectal cancer survivors
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion