Long-term costs of colorectal cancer treatment in Spain.

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Corral, Julietaca
• dc.contributor.author Castells, Xavierca
• dc.contributor.author Molins, Eduardca
• dc.contributor.author Chiarello, Pietroca
• dc.contributor.author Borràs, Josep M.ca
• dc.contributor.author Cots Reguant, Francescca
• dc.date.accessioned 2016-04-15T08:43:31Z
• dc.date.available 2016-04-15T08:43:31Z
• dc.date.issued 2016
• dc.description.abstract BACKGROUND: Assessing the long-term cost of colorectal cancer (CRC) increases our understanding of the disease burden. The aim of this paper is to estimate the long-term costs of CRC care by stage at diagnosis and phase of care in the Spanish National Health Service. METHODS: Retrospective study on resource use and direct medical cost of a cohort of 699 patients diagnosed and treated for CRC in 2000-2006, with follow-up until 30 June 2011, at Hospital del Mar (Barcelona). The Kaplan-Meier sample average estimator was used to calculate observed 11-year costs, which were then extrapolated to 16 years. Bootstrap percentile confidence intervals were calculated for the mean long-term cost per patient by stage. Phase-specific, long-term costs for the entire CRC cohort were also estimated. RESULTS: With regard to stage at diagnosis, the mean long-term cost per patient ranged from €20,708 (in situ) to €47,681 (stage III). The estimated costs increased at more advanced stages up to stage III and then substantially decreased in stage IV. In terms of treatment phase, the mean cost of the initial period represented 24.8 % of the total mean long-term cost, whereas the cost of continuing and advanced care phases represented 16.9 and 58.3 %, respectively. CONCLUSIONS: This study is the first to provide long-term cost estimates for CRC treatment, by stage at diagnosis and phase of care, based on data from clinical practice in Spain, and it will contribute useful information for future studies on cost-effectiveness and budget impact of different therapeutic innovations in Spain.ca
• dc.description.sponsorship The present work is framed within different research projects of the Cancer Strategy of Catalonia and Hospital del Mar, which have received competitive public funding from the Catalan Agency for Health Information, Assessment, and Quality (AQuAS) (AATRM-GENDECAT; No. 082152004), the Fund for Health Research (FIS, PI 060990), and the Cancer Research Network (RTICC, RD 12/0036/0053) of the Carlos III Institute of Health (Instituto de Salud Carlos III/ISCIII) (co-funded by FEDER funds/European Regional Development Funds, ERDF), and the Agència de Gestió d'Ajuts Universitaris i de Recerca (AGAUR, 2014SGR0635)
• dc.format.mimetype application/pdfca
• dc.identifier.citation Corral J, Castells X, Molins E, Chiarello P, Borras JM, Cots F. Long-term costs of colorectal cancer treatment in Spain. BMC Health Serv Res. 2016 Feb 16;16(1):56. doi: 10.1186/s12913-016-1297-6.ca
• dc.identifier.doi http://dx.doi.org/10.1186/s12913-016-1297-6
• dc.identifier.issn 1472-6963
• dc.identifier.uri http://hdl.handle.net/10230/26101
• dc.language.iso engca
• dc.publisher BioMed Centralca
• dc.relation.ispartof BMC Health Services Research. 2016 Feb 16;16(1):56
• dc.rights © 2016 Corral et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/ca
• dc.subject.other Còlon -- Càncerca
• dc.subject.other Assistència mèdica -- Costosca
• dc.title Long-term costs of colorectal cancer treatment in Spain.ca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/publishedVersionca