Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial

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  • dc.contributor.author Jiménez Marrero, Santiago
  • dc.contributor.author Yun, Sergi
  • dc.contributor.author Cainzos-Achirica, Miguel
  • dc.contributor.author Enjuanes Grau, Cristina
  • dc.contributor.author Garay, Alberto
  • dc.contributor.author Farré López, Núria
  • dc.contributor.author Verdú-Rotellar, José María
  • dc.contributor.author Linas Alonso, Ana Maria
  • dc.contributor.author Ruiz-Rodriguez, María del Pilar
  • dc.contributor.author Hidalgo, Encarnacion
  • dc.contributor.author Calero; Esther
  • dc.contributor.author Comín Colet, Josep
  • dc.date.accessioned 2019-07-25T07:43:01Z
  • dc.date.available 2019-07-25T07:43:01Z
  • dc.date.issued 2018
  • dc.description.abstract Background The efficacy of telemedicine in the management of patients with chronic heart failure and left ventricular ejection fraction ≥40% is poorly understood. The aim of our analysis was to evaluate the efficacy of a telemedicine-based intervention specifically in these patients, as compared to standard of care alone. Methods The Insuficiència Cardiaca Optimització Remota (iCOR) study was a single centre, randomised, controlled trial, designed to evaluate a telemedicine intervention added to an existing hospital/primary care multidisciplinary, integrated programme for chronic heart failure patients. 178 participants were randomised to telemedicine or usual care, and were followed for six months. For the present sub-analysis, only iCOR participants (n = 116) with left ventricular ejection fraction ≥40% were included. The primary study endpoint was the incidence of an acute non-fatal heart failure event, defined as a new episode of worsening of symptoms and signs consistent with acute heart failure requiring intravenous diuretic therapy. The healthcare-related costs in each study group were also evaluated. Results The incidence of the first occurrence of the primary endpoint was significantly lower in the telemedicine arm (22% vs 56%, p<0.001), with a hazard ratio of 0.33 comparing to the usual care arm (95% confidence interval 0.17-0.64). Telemedicine was also associated with lower mean overall chronic heart failure care-related costs compared to usual care (8163€ vs 4993€, p=0.001). The results were consistent in both left ventricular ejection fraction of 40-49% and left ventricular ejection fraction ≥50% patients. Conclusions Our results suggest that telemedicine is a promising strategy for the management of chronic heart failure patients with left ventricular ejection fraction ≥40%. These findings should be replicated in larger cohorts.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Jiménez-Marrero S, Yun S, Cainzos-Achirica M, Enjuanes C, Garay A, Farre N. et al. Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial. J Telemed Telecare. 2020; 26(1-2): 64-72. DOI: 10.1177/1357633X18796439
  • dc.identifier.doi http://dx.doi.org/10.1177/1357633X18796439
  • dc.identifier.issn 1357-633X
  • dc.identifier.uri http://hdl.handle.net/10230/42170
  • dc.language.iso eng
  • dc.publisher SAGE Publications
  • dc.rights Jiménez-Marrero S, Yun S, Cainzos-Achirica M, Enjuanes C, Garay A, Farre N. et al. Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial. J Telemed Telecare. 2018 Sep 7:1357633X18796439. Copyright © 2018 (Copyright Holder). DOI: 10.1177/1357633X18796439.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.subject.keyword Chronic heart failure
  • dc.subject.keyword Heart failure
  • dc.subject.keyword Telemedicine
  • dc.title Impact of telemedicine on the clinical outcomes and healthcare costs of patients with chronic heart failure and mid-range or preserved ejection fraction managed in a multidisciplinary chronic heart failure programme: a sub-analysis of the iCOR randomized trial
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/acceptedVersion