GENCODE reference annotation for the human and mouse genomes

Mostra el registre complet Registre parcial de l'ítem

  • dc.contributor.author Frankish, Adam
  • dc.contributor.author Carbonell Sala, Silvia
  • dc.contributor.author Lagarde, Julien
  • dc.contributor.author Guigó Serra, Roderic
  • dc.date.accessioned 2019-03-12T08:41:05Z
  • dc.date.available 2019-03-12T08:41:05Z
  • dc.date.issued 2019
  • dc.description.abstract The accurate identification and description of the genes in the human and mouse genomes is a fundamental requirement for high quality analysis of data informing both genome biology and clinical genomics. Over the last 15 years, the GENCODE consortium has been producing reference quality gene annotations to provide this foundational resource. The GENCODE consortium includes both experimental and computational biology groups who work together to improve and extend the GENCODE gene annotation. Specifically, we generate primary data, create bioinformatics tools and provide analysis to support the work of expert manual gene annotators and automated gene annotation pipelines. In addition, manual and computational annotation workflows use any and all publicly available data and analysis, along with the research literature to identify and characterise gene loci to the highest standard. GENCODE gene annotations are accessible via the Ensembl and UCSC Genome Browsers, the Ensembl FTP site, Ensembl Biomart, Ensembl Perl and REST APIs as well as https://www.gencodegenes.org.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Frankish A, Diekhans M, Ferreira AM, Johnson R, Jungreis I, Loveland J et al. GENCODE reference annotation for the human and mouse genomes. Nucleic Acids Res. 2019;47(D1):D766-D773. DOI: 10.1093/nar/gky955
  • dc.identifier.doi http://dx.doi.org/10.1093/nar/gky955
  • dc.identifier.issn 0305-1048
  • dc.identifier.uri http://hdl.handle.net/10230/36799
  • dc.language.iso eng
  • dc.publisher Oxford University Press
  • dc.relation.ispartof Nucleic Acids Research. 2019;47(D1):D766-D773
  • dc.rights © The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly c
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.title GENCODE reference annotation for the human and mouse genomes
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

Col·leccions

Articles (Center for Genomic Regulation (CRG))
Articles (Departament de Medicina i Ciències de la Vida)