The genomic history of the Aegean palatial civilizations

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  • dc.contributor.author Clemente, Florian
  • dc.contributor.author Dolgova, Olga
  • dc.contributor.author Lao Grueso, Oscar, 1976-
  • dc.contributor.author Papageorgopoulou, Christina
  • dc.date.accessioned 2021-05-28T06:24:38Z
  • dc.date.available 2021-05-28T06:24:38Z
  • dc.date.issued 2021
  • dc.description.abstract The Cycladic, the Minoan, and the Helladic (Mycenaean) cultures define the Bronze Age (BA) of Greece. Urbanism, complex social structures, craft and agricultural specialization, and the earliest forms of writing characterize this iconic period. We sequenced six Early to Middle BA whole genomes, along with 11 mitochondrial genomes, sampled from the three BA cultures of the Aegean Sea. The Early BA (EBA) genomes are homogeneous and derive most of their ancestry from Neolithic Aegeans, contrary to earlier hypotheses that the Neolithic-EBA cultural transition was due to massive population turnover. EBA Aegeans were shaped by relatively small-scale migration from East of the Aegean, as evidenced by the Caucasus-related ancestry also detected in Anatolians. In contrast, Middle BA (MBA) individuals of northern Greece differ from EBA populations in showing ∼50% Pontic-Caspian Steppe-related ancestry, dated at ca. 2,600-2,000 BCE. Such gene flow events during the MBA contributed toward shaping present-day Greek genomes.
  • dc.description.sponsorship We thank the INCD (https://incd.pt/) for use of their computing infrastructure, which is funded by FCT and FEDER ( 01/SAICT/2016 022153 ).C.P., E.G., A.S., L.W., and J. Burger acknowledge the support of the European Union and the General Secretariat of Research and Innovation-GSRI, Ministry of Development & Investments in Greece, and the Federal Ministry of Education and Research-BMBF in Germany under the Bilateral Cooperation Program Greece – Germany 2017 (project BIOMUSE-0195 ). O.L. and O. Dolgova acknowledge the support of the Spanish Ministry of Science and Innovation to the EMBL partnership, Centro de Excelencia Severo Ochoa, CERCA Programme/Generalitat de Catalunya, Spanish Ministry of Science and Innovation through the Instituto de Salud Carlos III, Generalitat de Catalunya through Departament de Salut and Departament d’Empresa i Coneixement, as well as co-financing with funds from the European Regional Development Fund by the Spanish Ministry of Science and Innovation corresponding to the Programa Operativo FEDER Plurirregional de España (POPE) 2014-2020, and by the Secretaria d’Universitats i Recerca, Departament d’Empresa i Coneixement of the Generalitat de Catalunya corresponding to the Programa Operatiu FEDER de Catalunya 2014-2020. F.C., C.E.G.A., S.N., D.I.C.D., L.A., B.S.d.M., Y.O.A.C., F.M., J.V.M.-M., and A.-S.M. were supported by the Swiss National Science Foundation (SFNS) and a European Research Council (ERC) grant to A.-S.M. M.U., S.T., D.U.-K., and C.P. were co-financed by the EU Social Fund and the Greek national funds research funding program ARISTEIA II ( project-3461 ). C.P., E.G., A.S., L.W., and J. Burger were co-financed by the Greek-German bilateral cooperation program 2017 (General Secreteriat for Research and Innovation, Ministry of Development and Investments, Greece, and Federal Ministry of Education and Research - BMBF, Germany) project BIOMUSE-0195 funded by the Operational Programme “Competitiveness, Entrepreneurship and Innovation” (NSRF 2014-2020 ) and co-financed by Greece and the European Union (EU Social Fund and European Regional Development Fund). E.K. was funded by the Greek State Scholarships Foundation (IKY). O. Delaneau is funded by a SNSF (project grant PP00P3_176977 ). V.C.S. was supported by Portuguese Foundation for Science and Technology (FCT-Fundação para a Ciência e Tecnologia) through funds granted to cE3c ( UIDB/00329/2020 ) and individual grant CEECIND/02391/2017 . O.L. was supported by a Ramón y Cajal grant from the Spanish Ministerio de Economia y Competitividad (MEIC) (RYC-2013-14797), a PGC2018-098574-B-I00 (MEIC/FEDER) grant, and the support of Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement de la Generalitat de Catalunya ( GRC 2017 SGR 937 ). O. Dolgova was supported by a PGC2018-098574-B-I00 (MEIC/FEDER) grant. J.D.J. was funded by National Institutes of Health grants R01GM135899 and R35GM139383
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Clemente F, Unterländer M, Dolgova O, Amorim CEG, Coroado-Santos F, Neuenschwander S et al. The genomic history of the Aegean palatial civilizations. Cell. 2021 May 13;184(10):2565-2586.e21. DOI: 10.1016/j.cell.2021.03.039
  • dc.identifier.doi http://dx.doi.org/10.1016/j.cell.2021.03.039
  • dc.identifier.issn 0092-8674
  • dc.identifier.uri http://hdl.handle.net/10230/47677
  • dc.language.iso eng
  • dc.publisher Elsevier
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/RYC-2013-14797
  • dc.rights © 2021 Florian Clemente et al. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
  • dc.subject.other Genòmica
  • dc.subject.other Genètica
  • dc.subject.other Civilitzacions palacials de l'Egeu
  • dc.title The genomic history of the Aegean palatial civilizations
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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