Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era: beyond myocardial mechanical reperfusion

Mostra el registre complet Registre parcial de l'ítem

• dc.contributor.author Ribas Barquet, Núriaca
• dc.contributor.author García-García, Cosmeca
• dc.contributor.author Meroño, Oonaca
• dc.contributor.author Recasens, Lluísca
• dc.contributor.author Pérez-Fernández, Silviaca
• dc.contributor.author Bazán, Víctorca
• dc.contributor.author Salvatella Giralt, Neusca
• dc.contributor.author Martí-Almor, Julioca
• dc.contributor.author Bruguera-Cortada, Jordica
• dc.contributor.author Elosua Llanos, Robertoca
• dc.date.accessioned 2017-07-13T06:48:37Z
• dc.date.available 2017-07-13T06:48:37Z
• dc.date.issued 2017
• dc.description.abstract Background: The AMI code is a regional network enhancing a rapid and widespread access to reperfusion therapy (giving priority to primary angioplasty) in patients with acute ST-segment elevation myocardial infarction (STEMI). We aimed to assess the long-term control of conventional cardiovascular risk factors after a STEMI among patients included in the AMI code registry. Design and methods: Four hundred and fifty-four patients were prospectively included between June-2009 and April-2013. Clinical characteristics were collected at baseline. The long-term control of cardiovascular risk factors and cardiovascular morbidity/mortality was assessed among the 6-months survivors. Results: A total of 423 patients overcame the first 6 months after the STEMI episode, of whom 370 (87%) underwent reperfusion therapy (363, 98% of them, with primary angioplasty). At 1-year follow-up, only 263 (62%) had adequate blood pressure control, 123 (29%) had LDL-cholesterol within targeted levels, 126/210 (60%) smokers had withdrawn from their habit and 40/112 (36%) diabetic patients had adequate glycosylated hemoglobin levels. During a median follow-up of 20 (11–30) months, cumulative mortality of 6 month-survivors was 6.1%, with 9.9% of hospital cardiovascular readmissions. The lack of assessment of LDL and HDL-cholesterol were significantly associated with higher mortality and cardiovascular readmission rates. Conclusions: Whereas implementation of the AMI code resulted in a widespread access to rapid reperfusion therapy, its long-term therapeutic benefit may be partially counterbalanced by a manifestly suboptimal control of cardiovascular risk factors. Further efforts should be devoted to secondary prevention strategies after STEMI.
• dc.description.sponsorship This work was supported by grant from Instituto de Salud Carlos III FEDER (Programa HERACLES RD12/0042/0013).
• dc.format.mimetype application/pdfca
• dc.identifier.citation Ribas Barquet N, García-García C, Meroño O, Recasens L, Pérez-Fernández S, Bazán V, Salvatella Giralt N, Martí-Almor J, Bruguera-Cortada J, Elosua Llanos R. Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era: beyond myocardial mechanical reperfusion. BMC Cardiovascular Disorders. 2017; 17(1): 54. DOI: 10.1186/s12872-017-0493-6
• dc.identifier.doi http://dx.doi.org/10.1186/s12872-017-0493-6
• dc.identifier.issn 1471-2261
• dc.identifier.uri http://hdl.handle.net/10230/32532
• dc.language.iso eng
• dc.publisher BioMed Centralca
• dc.relation.ispartof BMC Cardiovascular Disorders. 2017; 17(1): 54
• dc.rights © Ribas N, García-García C, Meroño O, Recasens L, Pérez-Fernández S, Bazán V, Salvatella N, Martí-Almor J, Bruguera J, Elosua Llanos R. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword ST-segment elevation myocardial infarction
• dc.subject.keyword Coronary angioplasty
• dc.subject.keyword Secondary prevention
• dc.subject.keyword Prognosis
• dc.subject.keyword Reperfusion therapy
• dc.subject.keyword Cardiovascular risk factors
• dc.title Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era: beyond myocardial mechanical reperfusionca
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion