Validity of a method for the self-screening of cardiovascular risk

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• dc.contributor.author Barroso, María
• dc.contributor.author Pérez-Fernández, Silvia
• dc.contributor.author Vila, M. Mar
• dc.contributor.author Zomeño Fajardo, Maria Dolores
• dc.contributor.author Martí-Lluch, Ruth
• dc.contributor.author Cordón, Ferran
• dc.contributor.author Ramos, Rafel
• dc.contributor.author Elosua Llanos, Roberto
• dc.contributor.author Dégano, Irene R.
• dc.contributor.author Fitó Colomer, Montserrat
• dc.contributor.author Cabezas, Carmen
• dc.contributor.author Salvador, Gemma
• dc.contributor.author Castell, Conxa
• dc.contributor.author Grau Magaña, Maria
• dc.date.accessioned 2019-03-27T08:44:49Z
• dc.date.available 2019-03-27T08:44:49Z
• dc.date.issued 2018
• dc.description.abstract BACKGROUND: The validity of a cardiovascular risk self-screening method was assessed. The results obtained for self-measurement of blood pressure, a point-of-care system's assessment of lipid profile and glycated hemoglobin, and a self-administered questionnaire (sex, age, diabetes, tobacco consumption) were compared with the standard screening (gold standard) conducted by a health professional. METHODS: Crossover clinical trial on a population-based sample from Girona (north-eastern Spain), aged 35-74, with no cardiovascular disease at recruitment. Participants were randomized to one of the two risk assessment sequences (standard screening followed by self-screening or vice versa). Cardiovascular risk was estimated with the Framingham-REGICOR function. Concordance between methods was estimated with the intraclass correlation coefficient (ICC). Sensitivity, specificity, and positive and negative predictive values were estimated, considering 5% cardiovascular risk as the cutoff point. ClinicalTrials.gov Registration #NCT02373319. Clinical Research Ethic Committee of the Parc de Salut Mar Registration #2014/5815/I. RESULTS: The median cardiovascular risk in men was 2.56 (interquartile range: 1.42-4.35) estimated by standard methods and 2.25 (1.28-4.07) by self-screening with ICC=0.92 (95% CI: 0.90-0.93). In women, the cardiovascular risk was 1.14 (0.61-2.10) by standard methods and 1.10 (0.56-2.00) by self-screening, with ICC=0.89 (0.87-0.90). The sensitivity, specificity, and positive and negative predictive values for the self-screening method were 0.74 (0.63-0.82), 0.97 (0.95-0.99), 0.86 (0.77-0.93), and 0.94 (0.91-0.96), respectively, in men. In women, these values were 0.50 (0.30-0.70), 0.99 (0.98-1), 0.81 (0.54-0.96), and 0.97 (0.95-0.99), respectively. CONCLUSION: The self-screening method for assessing cardiovascular risk provided similar results to the standard method. Self-screening had high clinical performance to rule out intermediate or high cardiovascular risk.
• dc.format.mimetype application/pdf
• dc.identifier.citation Barroso M, Pérez-Fernández S, Vila MM, Zomeño MD, Martí-Lluch R, Cordon F. et al. Validity of a method for the self-screening of cardiovascular risk. Clin Epidemiol. 2018 May 10;10:549-560. DOI: 10.2147/CLEP.S158358
• dc.identifier.doi http://dx.doi.org/10.2147/CLEP.S158358
• dc.identifier.issn 1179-1349
• dc.identifier.uri http://hdl.handle.net/10230/36979
• dc.language.iso eng
• dc.publisher Dove Medical Press
• dc.relation.ispartof Clinical Epidemiology. 2018 May 10;10:549-60
• dc.rights © 2018 Barroso et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by-nc/3.0/
• dc.subject.keyword Cardiovascular diseases
• dc.subject.keyword Empowerment
• dc.subject.keyword Epidemiology
• dc.subject.keyword Preventive medicine
• dc.subject.keyword Public health
• dc.subject.keyword Risk assessment
• dc.subject.other Cor -- Malalties -- Epidemiologia
• dc.title Validity of a method for the self-screening of cardiovascular risk
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion