Effect of different types of supervised exercise programs on cardiorespiratory and muscular fitness, pain, fatigue, mental health and inflammatory and oxidative stress biomarkers in older patients with post-COVID-19 sequelae “EJerSA-COVID-19”: a randomized controlled trial

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• dc.contributor.author Pleguezuelos Cobo, Eulogio
• dc.contributor.author Sánchez-Nuño, Sergio
• dc.contributor.author Del Carmen, Amin
• dc.contributor.author Serra-Payá, Noemí
• dc.contributor.author Moreno, Eva
• dc.contributor.author Molina Raya, Lorena, 1979-
• dc.contributor.author Robleda, Gemma
• dc.contributor.author Benet Blasco, Marta
• dc.contributor.author Santos-Ruiz, Susana
• dc.contributor.author Biurrun Garrido, Ainoa
• dc.contributor.author Jerez-Molina, Carmen
• dc.contributor.author Miravitlles, Marc
• dc.contributor.author Serra-Prat, Mateu
• dc.contributor.author Viñals Álvarez, Xavier, 1985-
• dc.contributor.author Girabent Farrés, Montserrat
• dc.contributor.author Carbonell, Teresa
• dc.contributor.author Garnacho-Castaño, Manuel V.
• dc.date.accessioned 2025-05-05T06:17:24Z
• dc.date.available 2025-05-05T06:17:24Z
• dc.date.issued 2023
• dc.description.abstract Background. Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant exercise intolerance. This study aims to investigate the effects of different exercise programs on physical and mental fitness, physical condition and biomarkers of the immune system and oxidative stress in older patients with post-COVID-19 sequelae. Methods. The sample will be made up of 120 eligible participants, over the age of 60 years who have had COVID-19 disease and are survivors and present persistent COVID-19 symptomatology diagnosed by the corresponding physician. The participants will be randomly assigned to the experimental groups: supervised endurance group (SEG, n = 30), supervised strength group (SSG, n = 30), supervised concurrent group (SCG, n = 30), which will perform the corresponding exercise program 3 days a week compared to the control group (CG, n = 30), which will not carry out a supervised exercise program. The design of this project will include measurements of four relevant dimensions; 1) Cardiorespiratory fitness; 2) Muscle fitness; 3) Pain and mental health; and 4) Biomarkers of inflammation and oxidative stress. Conclusions. The results of this study will provide insights into the effects of different exercise programs on physical and mental fitness, physical condition and biomarkers of the immune system and oxidative stress in older patients with post-COVID-19 sequelae. These findings may be the basis for the formulation of health plans and rehabilitation programs that allow healthy aging and a reduction in the associated morbidity in patients with post-COVID-19 sequelae.en
• dc.format.mimetype application/pdf
• dc.identifier.citation Pleguezuelos E, Sánchez-Nuño S, Del Carmen A, Serra-Payá N, Moreno E, Molina-Raya L, et al. Effect of different types of supervised exercise programs on cardiorespiratory and muscular fitness, pain, fatigue, mental health and inflammatory and oxidative stress biomarkers in older patients with post-COVID-19 sequelae “EJerSA-COVID-19”: a randomized controlled trial. BMC Geriatr. 2023 Dec 15;23(1):1-12. DOI: 10.1186/s12877-023-04544-3
• dc.identifier.doi http://dx.doi.org/10.1186/s12877-023-04544-3
• dc.identifier.issn 1471-2318
• dc.identifier.uri http://hdl.handle.net/10230/70273
• dc.language.iso eng
• dc.publisher BioMed Central
• dc.relation.ispartof BMC Geriatrics. 2023 Dec 15;23(1):1-12
• dc.rights © [Author(s)]. Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Rehabilitation programsen
• dc.subject.keyword Endurance exerciseen
• dc.subject.keyword Resistance exerciseen
• dc.subject.keyword Cardiopulmonary exercise testingen
• dc.subject.keyword Muscle strength assessmenten
• dc.subject.keyword Quality of lifeen
• dc.subject.keyword Older peopleen
• dc.subject.keyword SARS-CoV-2en
• dc.title Effect of different types of supervised exercise programs on cardiorespiratory and muscular fitness, pain, fatigue, mental health and inflammatory and oxidative stress biomarkers in older patients with post-COVID-19 sequelae “EJerSA-COVID-19”: a randomized controlled trialen
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion