Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperament

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  • dc.contributor.author Fernández Aranda, Fernandoca
  • dc.contributor.author Sauchelli, Sarahca
  • dc.contributor.author Pastor, Antonioca
  • dc.contributor.author González, Marcela L.ca
  • dc.contributor.author Torre Fornell, Rafael de laca
  • dc.contributor.author Granero, Roserca
  • dc.contributor.author Jiménez Murcia, Susanaca
  • dc.contributor.author Baños, Rosa M.ca
  • dc.contributor.author Botella, Cristinaca
  • dc.contributor.author Fernández Real, Jose M.ca
  • dc.contributor.author Fernández García, José C.ca
  • dc.contributor.author Frühbeck, Gemaca
  • dc.contributor.author Gómez Ambrosi, Javierca
  • dc.contributor.author Rodríguez, Roserca
  • dc.contributor.author Tinahones Madueño, Francisco Joséca
  • dc.contributor.author Arcelus, Jonca
  • dc.contributor.author Fagundo, Ana B.ca
  • dc.contributor.author Agüera, Zaidaca
  • dc.contributor.author Miró, Jordica
  • dc.contributor.author Casanueva, Felipe F.ca
  • dc.date.accessioned 2015-05-25T09:06:46Z
  • dc.date.available 2015-05-25T09:06:46Z
  • dc.date.issued 2014ca
  • dc.description.abstract Background: Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI) however no study has explored how these factors interact in females. The aims of this cross-sectional study were to 1) examine differences among distinct BMI groups on daytime physical activity and time spent in moderate-vigorous physical activity (MVPA), temperament traits and plasma endocannabinoid concentrations; and 2) explore the association and interaction between MVPA, temperament, endocannabinoids and BMI. Methods: Physical activity was measured with the wrist-worn accelerometer Actiwatch AW7, in a sample of 189 female participants (43 morbid obese, 30 obese, and 116 healthy-weight controls). The Temperament and Character Inventory-Revised questionnaire was used to assess personality traits. BMI was calculated by bioelectrical impedance analysis via the TANITA digital scale. Blood analyses were conducted to measure levels of endocannabinoids and endocannabinoid-related compounds. Path-analysis was performed to examine the association between predictive variables and MVPA. Results: Obese groups showed lower MVPA and dysfunctional temperament traits compared to healthy-weight controls. Plasma concentrations of 2-arachidonoylglyceryl (2-AG) were greater in obese groups. Path-analysis identified a direct effect between greater MVPA and low BMI (b = −0.13, p = .039) and high MVPA levels were associated with elevated anandamide (AEA) levels (b = 0.16, p = .049) and N-oleylethanolamide (OEA) levels (b = 0.22, p = .004), as well as high Novelty seeking (b = 0.18, p<.001) and low Harm avoidance (b = −0.16, p<.001). Conclusions: Obese individuals showed a distinct temperament profile and circulating endocannabinoids compared to controls. Temperament and endocannabinoids may act as moderators of the low MVPA in obesity.en
  • dc.description.sponsorship This manuscript was supported by grants from Instituto Salud Carlos III (FIS PI11/210 and CIBERobn) and DIUE de la Generalitat de Catalunya (2009 SGR 718), Spain. CIBERObn is an initiative of ISCIII. Sarah Sauchelli is recipient of a pre-doctoral Grant (2013–17) by IDIBELL. Jose C. Fernández-García is recipient of a ‘Rio Hortega’ contract from ‘Instituto de Salud Carlos III’, Madrid, Spain (CM12/00059).en
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Fernández-Aranda F, Sauchelli S, Pastor A, González ML, De La Torre R, Granero R et al. Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperament. PLoS ONE. 2014;9(8):e104534. DOI: 10.1371/journal.pone.0104534ca
  • dc.identifier.doi http://dx.doi.org/10.1371/journal.pone.0104534
  • dc.identifier.issn 1932-6203ca
  • dc.identifier.uri http://hdl.handle.net/10230/23644
  • dc.language.iso engca
  • dc.publisher Public Library of Science (PLoS)ca
  • dc.relation.ispartof PLoS ONE. 2014;9(8):e104534
  • dc.rights © 2014 Fernández-Aranda et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri https://creativecommons.org/licenses/by/4.0/
  • dc.subject.other Obesitatca
  • dc.title Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperamenten
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca

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