Health-related quality of life (HRQOL) and its associated factors in children with Type 1 Diabetes Mellitus (T1DM)

Murillo, Marta; Bel, Joan; Pérez, Jacobo; Corripio, Raquel; Carreras, Gemma; Herrero, Xavier; Mengibar, Josep-Maria; Rodriguez-Arjona, Dolors; Ravens-Sieberer, Ulrike; Raat, Hein; Rajmil Rajmil, Luis Alberto

Health-related quality of life (HRQOL) and its associated factors in children with Type 1 Diabetes Mellitus (T1DM)

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dc.contributor.author Murillo, Martaca
dc.contributor.author Bel, Joanca
dc.contributor.author Pérez, Jacoboca
dc.contributor.author Corripio, Raquelca
dc.contributor.author Carreras, Gemmaca
dc.contributor.author Herrero, Xavierca
dc.contributor.author Mengibar, Josep-Mariaca
dc.contributor.author Rodriguez-Arjona, Dolorsca
dc.contributor.author Ravens-Sieberer, Ulrikeca
dc.contributor.author Raat, Heinca
dc.contributor.author Rajmil Rajmil, Luis Albertoca
dc.date.accessioned 2017-07-14T07:21:55Z
dc.date.available 2017-07-14T07:21:55Z
dc.date.issued 2017
dc.description.abstract Background: The objective of the study was to describe the baseline health-related quality of life (HRQOL) in a cohort of children and adolescents with type 1 diabetes mellitus (T1DM), and analyze its associated clinical and sociodemographic factors, assessing HRQOL through internet. Methods: This was a descriptive study of 136 patients with T1DM from 5 hospitals in Catalonia, Spain (72 girls, mean age 13.4 years (range 8–19). Inclusion criteria were more than 6 months from diagnosis, more than 8 years old and without cognitive problems. Sociodemographic (age, sex, family level of education, type of family and origin) and clinical variables (type of insulin therapy, duration of disease, adherence to treatment, body mass index and HbA1c) were collected. HRQOL was assessed using the EuroQol-5D (EQ-5D-Y) and KIDSCREEN, collected via web. Mental health status was assessed using the Strengths and Difficulties Questionnaire. Multiple linear regression models were adjusted. Results: Physical-well-being mean scores were lower (worse) than the European average (<50) and especially in girls, older children (>11 years old), those from single-parent families, and those with low adherence. Older children and patients with poor metabolic control (HbA1c >7,5% [58 mmol/mol]) showed worse scores in the KIDSCREEN-10 index. Similar results were observed with the EQ-5D-Y. Multivariate models showed that age, single-parent families, adherence and mental health were the most influential factors. Conclusions: Diabetic patients report similar HRQOL than the population of the same age with slightly worse physical well-being. The study shows some factors to be taken into account to improve HRQOL, and also the feasibility of using web to collect information in clinical practice.
dc.description.sponsorship The study was partially funded by Fondo de Investigación Sanitaria, Spanish Ministry of Health, contract N° 12/01296.
dc.format.mimetype application/pdfca
dc.identifier.citation Murillo M, Bel J, Pérez J, Corripio R, Carreras G, Herrero X, Mengibar J-M, Rodriguez-Arjona D, Ravens-Sieberer U, Raat H, Rajmil Rajmil LA. Health-related quality of life (HRQOL) and its associated factors in children with Type 1 Diabetes Mellitus (T1DM). BMC Pediatrics. 2017; 17(1): 16. DOI: 10.1186/s12887-017-0788-x
dc.identifier.doi http://dx.doi.org/10.1186/s12887-017-0788-x
dc.identifier.issn 1471-2431
dc.identifier.uri http://hdl.handle.net/10230/32541
dc.language.iso eng
dc.publisher BioMed Centralca
dc.relation.ispartof BMC Pediatrics. 2017; 17(1): 16
dc.rights © 2017 Marta Murillo et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.subject.keyword Adolescents
dc.subject.keyword Children
dc.subject.keyword Health-related quality of life
dc.subject.keyword Pediatric
dc.subject.keyword Type 1 diabetes
dc.title Health-related quality of life (HRQOL) and its associated factors in children with Type 1 Diabetes Mellitus (T1DM)ca
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/publishedVersion

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