What is a bladder cancer molecular subtype? – Counterpoint
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- dc.contributor.author Radvanyi, François
- dc.contributor.author Real, Francisco X.
- dc.contributor.author McConkey, David
- dc.date.accessioned 2024-02-05T14:01:21Z
- dc.date.available 2024-02-05T14:01:21Z
- dc.date.issued 2023
- dc.description.abstract In an accompanying paper, Mattias Hoglund discusses on what is a bladder cancer molecular subtype. He emphasizes the need to consider the aim of tumor classification, which is obviously critical to the approach. He also focuses on considering primarily the identity features of the neoplastic cells. Here, we provide a counterpoint. While largely agreeing with his views, we underline that other parameters that may vary in a spatial or temporal scale, and the tumor microenvironment, can also provide relevant information to render tumor classifications clinically useful. Furthermore, tumor heterogeneity and evolution during the disease course - natural or under therapeutic pressure - should be considered.
- dc.format.mimetype application/pdf
- dc.identifier.citation Radvanyi F, Real FX, McConkey D. What is a bladder cancer molecular subtype? - Counterpoint. Bladder Cancer. 2023;9(4):299-304. DOI: 10.3233/BLC-230059
- dc.identifier.doi http://dx.doi.org/10.3233/BLC-230059
- dc.identifier.issn 2352-3727
- dc.identifier.uri http://hdl.handle.net/10230/58952
- dc.language.iso eng
- dc.publisher IOS Press
- dc.relation.ispartof Bladder Cancer. 2023;9(4):299-304
- dc.rights © 2023 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
- dc.subject.keyword Bladder cancer
- dc.subject.keyword Molecular subtypes
- dc.subject.keyword Tumor classification
- dc.subject.keyword Genomics
- dc.subject.keyword Tumor microenvironment
- dc.subject.keyword Prediction of outcome
- dc.title What is a bladder cancer molecular subtype? – Counterpoint
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion