Gender analysis of the frequency and course of depressive disorders and relationship with personality traits in general population: A prospective cohort study

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• dc.contributor.author Serrano, Domènec
• dc.contributor.author Martí-Lluch, Ruth
• dc.contributor.author Cárdenas, Mérida
• dc.contributor.author Solanas, Pascual
• dc.contributor.author Marrugat de la Iglesia, Jaume
• dc.contributor.author Vilalta-Franch, Joan
• dc.contributor.author Garre-Olmo, Josep
• dc.date.accessioned 2022-09-28T06:15:31Z
• dc.date.available 2022-09-28T06:15:31Z
• dc.date.issued 2022
• dc.description.abstract Background: We aimed to determine the prevalence and course of subthreshold depressive symptomatology (sDS) and probable major depressive episode (MDE) and to examine their association with personality traits among men and women. Methods: A community-based sample aged 35 years or older was examined in two waves (median follow-up of 6.9 years). The Patient Health Questionnaire-9 (PHQ-9) was used to assess sDS and MDE. The 10-item version of the Big Five Inventory was used to assess personality traits. Prevalence was assessed at baseline (n = 5,557) and incidence and persistence-recurrence rates were computed at follow up (n = 3,102). Logistic regression models were adjusted to explore the association of personality traits with prevalence and course of depressive disorders. Results: The prevalence of sDS and MDE was 14.04% (95% CI = 17.04-19.08) and 8.54 (95% CI=7.82-9.31), the incidence was 14.30 per 1,000 person-years (95% CI=12.49-16.31) and 4.34 per 1,000 person-years (95% CI=3.46-5.36), and the persistence-recurrence was 35.04 per 1,000 person-years (95% CI=29.00-41.96) and 28.8 per 1,000 person-years (95% CI=20.49-38.14). The gender gap was higher for MDE. Personality traits were differentially associated with the prevalence and course of depressive disorders between men and women. Limitations: Because this study used questionnaires to assess depressive disorders and personality traits, information bias could not be ruled out. Conclusions: The gender gap was higher for the prevalence and course of the probable MDE. There were more personality traits related with the course of the sDS and they had a major role in the course of the probable MDE in women.
• dc.format.mimetype application/pdf
• dc.identifier.citation Serrano D, Martí-Lluch R, Cárdenas M, Solanas P, Marrugat J, Vilalta-Franch J, Garre-Olmo J. Gender analysis of the frequency and course of depressive disorders and relationship with personality traits in general population: A prospective cohort study. J Affect Disord. 2022 Apr 1;302:241-8. DOI: 10.1016/j.jad.2022.01.088
• dc.identifier.doi http://dx.doi.org/10.1016/j.jad.2022.01.088
• dc.identifier.issn 0165-0327
• dc.identifier.uri http://hdl.handle.net/10230/54183
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof J Affect Disord. 2022 Apr 1;302:241-8
• dc.rights © 2022 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Depression
• dc.subject.keyword Epidemiology
• dc.subject.keyword Personality
• dc.subject.keyword Population
• dc.subject.keyword Sex differences
• dc.title Gender analysis of the frequency and course of depressive disorders and relationship with personality traits in general population: A prospective cohort study
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion