Exercise Intolerance in post-acute sequelae of COVID-19 and the value of cardiopulmonary exercise testing- a mini-review

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• dc.contributor.author Aparisi, Álvaro
• dc.contributor.author Ladrón, Raquel
• dc.contributor.author Ybarra-Falcón, Cristina
• dc.contributor.author Tobar, Javier
• dc.contributor.author San Román, J. Alberto
• dc.date.accessioned 2023-02-10T07:28:04Z
• dc.date.available 2023-02-10T07:28:04Z
• dc.date.issued 2022
• dc.description.abstract Coronavirus disease (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with systemic organ damage in the most severe forms. Long-term complications of SARS-CoV-2 appear to be restricted to severe presentations of COVID-19, but many patients with persistent symptoms have never been hospitalized. Post-acute sequelae of COVID-19 (PASC) represents a heterogeneous group of symptoms characterized by cardiovascular, general, respiratory, and neuropsychiatric sequelae. The pace of evidence acquisition with PASC has been rapid, but the mechanisms behind it are complex and not yet fully understood. In particular, exercise intolerance shares some features with other classic respiratory and cardiac disorders. However, cardiopulmonary exercise testing (CPET) provides a comprehensive assessment and can unmask the pathophysiological mechanism behind exercise intolerance in gray-zone PASC. This mini-review explores the utility of CPET and aims to provide a comprehensive assessment of PASC by summarizing the current evidence.
• dc.format.mimetype application/pdf
• dc.identifier.citation Aparisi Á, Ladrón R, Ybarra-Falcón C, Tobar J, San Román JA. et al. Exercise Intolerance in post-acute sequelae of COVID-19 and the value of cardiopulmonary exercise testing- a mini-review. Front Med (Lausanne). 2022 Jul 22; 9: 924819. DOI: 10.3389/fmed.2022.924819
• dc.identifier.doi http://dx.doi.org/10.3389/fmed.2022.924819
• dc.identifier.issn 2296-858X
• dc.identifier.uri http://hdl.handle.net/10230/55708
• dc.language.iso eng
• dc.publisher Frontiers
• dc.rights Copyright © 2022 Aparisi, Ladrón, Ybarra-Falcón, Tobar and San Román. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) http://creativecommons.org/licenses/by/4.0/. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Autonomic dysfunction
• dc.subject.keyword Cardiopulmonary exercise testing
• dc.subject.keyword Exercise intolerance
• dc.subject.keyword Hyperventilation
• dc.subject.keyword Post-acute sequelae COVID-19
• dc.title Exercise Intolerance in post-acute sequelae of COVID-19 and the value of cardiopulmonary exercise testing- a mini-review
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion