Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19

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  • dc.contributor.author Karachaliou, Marianna
  • dc.contributor.author Ranzani, Otavio
  • dc.contributor.author Espinosa Díaz, Ana
  • dc.contributor.author Iraola Guzmán, Susana
  • dc.contributor.author Castaño Vinyals, Gemma
  • dc.contributor.author Vidal, Marta
  • dc.contributor.author Jiménez, Alfons
  • dc.contributor.author Bañuls, Marc
  • dc.contributor.author Alonso Nogués, Eva
  • dc.contributor.author Aguilar, Ruth
  • dc.contributor.author García Aymerich, Judith
  • dc.contributor.author Cid Ibeas, Rafael de
  • dc.contributor.author Dobaño, Carlota
  • dc.contributor.author Moncunill, Gemma
  • dc.contributor.author Kogevinas, Manolis
  • dc.date.accessioned 2024-11-13T07:08:19Z
  • dc.date.available 2024-11-13T07:08:19Z
  • dc.date.issued 2024
  • dc.description.abstract Limited research suggests that certain viruses reactivate in severe-acute-respiratory-syndrome-coronavirus 2 infection, contributing to the development of postacute sequelae of COVID-19 (PASC). We examined 1083 infected individuals from a population-based cohort, and assessed differences in plasma immunoglobulin (Ig)G and immunoglobulin A levels against Epstein-Barr virus (EBV), cytomegalovirus, varicella zoster virus (VZV), BK polyomavirus, KI polyomavirus, WU polyomavirus (WUPyV), respiratory syncytial virus, and Adv-36 according to the severity of previous COVID-19 and PASC history. Individuals who had experienced severe COVID-19 had higher antibody responses to latent viruses. Ever PASC, active persistent PASC, and PASC with neuropsychiatric symptoms were associated with higher immnoglobulin G to EBV early antigen-diffuse, VZV, and WUPyV even among individuals without previous severe COVID-19.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Karachaliou M, Ranzani O, Espinosa A, Iraola-Guzmán S, Castaño-Vinyals G, Vidal M, et al. Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19. J Med Virol. 2024 Sep;96(9):e29862. DOI: 10.1002/jmv.29862
  • dc.identifier.doi http://dx.doi.org/10.1002/jmv.29862
  • dc.identifier.issn 0146-6615
  • dc.identifier.uri http://hdl.handle.net/10230/68507
  • dc.language.iso eng
  • dc.publisher Wiley
  • dc.relation.ispartof J Med Virol. 2024 Sep;96(9):e29862
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/HE/101046314
  • dc.rights © 2024 The Author(s). Journal of Medical Virology published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.keyword COVID‐19
  • dc.subject.keyword Herpesviruses
  • dc.subject.keyword Long COVID
  • dc.subject.keyword Polyomaviruses
  • dc.subject.keyword Postacute sequelae of COVID‐19
  • dc.title Antibody responses to common viruses according to COVID-19 severity and postacute sequelae of COVID-19
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion