Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ

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  • dc.contributor.author Solé Morata, Neus, 1988-ca
  • dc.contributor.author Villaescusa, Patriciaca
  • dc.contributor.author García-Fernández, Carlaca
  • dc.contributor.author Font-Porterias, Neusca
  • dc.contributor.author Illescas, María Joséca
  • dc.contributor.author Valverde, Lauraca
  • dc.contributor.author Tassi, Francescaca
  • dc.contributor.author Ghirotto, Silviaca
  • dc.contributor.author Férec, Claudeca
  • dc.contributor.author Rouault, Karenca
  • dc.contributor.author Jiménez-Moreno, Susanaca
  • dc.contributor.author Martínez-Jarreta, Begoñaca
  • dc.contributor.author Pinheiro, María Fátimaca
  • dc.contributor.author Zarrabeitia, María T.ca
  • dc.contributor.author Carracedo, Ángelca
  • dc.contributor.author Pancorbo, Marian M. deca
  • dc.contributor.author Calafell i Majó, Francescca
  • dc.date.accessioned 2017-10-06T11:04:01Z
  • dc.date.available 2017-10-06T11:04:01Z
  • dc.date.issued 2017
  • dc.description.abstract Haplogroup R1b-M269 comprises most Western European Y chromosomes; of its main branches, R1b-DF27 is by far the least known, and it appears to be highly prevalent only in Iberia. We have genotyped 1072 R1b-DF27 chromosomes for six additional SNPs and 17 Y-STRs in population samples from Spain, Portugal and France in order to further characterize this lineage and, in particular, to ascertain the time and place where it originated, as well as its subsequent dynamics. We found that R1b-DF27 is present in frequencies ~40% in Iberian populations and up to 70% in Basques, but it drops quickly to 6-20% in France. Overall, the age of R1b-DF27 is estimated at ~4,200 years ago, at the transition between the Neolithic and the Bronze Age, when the Y chromosome landscape of W Europe was thoroughly remodeled. In spite of its high frequency in Basques, Y-STR internal diversity of R1b-DF27 is lower there, and results in more recent age estimates; NE Iberia is the most likely place of origin of DF27. Subhaplogroup frequencies within R1b-DF27 are geographically structured, and show domains that are reminiscent of the pre-Roman Celtic/Iberian division, or of the medieval Christian kingdoms.
  • dc.description.sponsorship Funding was provided by the Agencia Estatal de Investigación and Fondo Europeo de Desarollo Regional (FEDER) (grants CGL2013-44351-P, CGL2016-75389-P), by Agència de Gestió d’Ajuts Universitaris i de la Recerca (Generalitat de Catalunya) grant 2014 SGR 866, and by the Basque Government (IT-424-07). FT was supported by the ERC Advanced Grant Agreement No 295733, ‘LanGeLin’ project
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Solé-Morata N, Villaescusa P, García-Fernández C, Font-Porterias N, Illescas MJ, Valverde L. Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situ. Sci Rep. 2017 Aug 4;7(1):7341. DOI: 10.1038/s41598-017-07710-x
  • dc.identifier.doi http://dx.doi.org/10.1038/s41598-017-07710-x
  • dc.identifier.issn 2045-2322
  • dc.identifier.uri http://hdl.handle.net/10230/32873
  • dc.language.iso eng
  • dc.publisher Nature Publishing Groupca
  • dc.relation.ispartof Scientific Reports. 2017 Aug 4;7(1):7341
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/CGL2013-44351-P
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/CGL2016-75389-P
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/295733
  • dc.rights © Nature Publishing Group. http://dx.doi.org/10.1038/s41598-017-07710-x. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.subject.other Cromosoma Y
  • dc.subject.other Genòmica
  • dc.title Analysis of the R1b-DF27 haplogroup shows that a large fraction of Iberian Y-chromosome lineages originated recently in situca
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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