Y-chromosomal sequences of diverse Indian populations and the ancestry of the Andamanese

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• dc.contributor.author Mondal, Mayukh, 1989-ca
• dc.contributor.author Bergström, Andersca
• dc.contributor.author Xue, Yalica
• dc.contributor.author Calafell i Majó, Francescca
• dc.contributor.author Laayouni, Hafid, 1968-ca
• dc.contributor.author Casals López, Ferranca
• dc.contributor.author Majumder, Partha P.ca
• dc.contributor.author Tyler-Smith, Chrisca
• dc.contributor.author Bertranpetit, Jaume, 1952-ca
• dc.date.accessioned 2018-04-19T09:22:33Z
• dc.date.issued 2017
• dc.description.abstract We present 42 new Y-chromosomal sequences from diverse Indian tribal and non-tribal populations, including the Jarawa and Onge from the Andaman Islands, which are analysed within a calibrated Y-chromosomal phylogeny incorporating South Asian (in total 305 individuals) and worldwide (in total 1286 individuals) data from the 1000 Genomes Project. In contrast to the more ancient ancestry in the South than in the North that has been claimed, we detected very similar coalescence times within Northern and Southern non-tribal Indian populations. A closest neighbour analysis in the phylogeny showed that Indian populations have an affinity towards Southern European populations and that the time of divergence from these populations substantially predated the Indo-European migration into India, probably reflecting ancient shared ancestry rather than the Indo-European migration, which had little effect on Indian male lineages. Among the tribal populations, the Birhor (Austro-Asiatic-speaking) and Irula (Dravidian-speaking) are the nearest neighbours of South Asian non-tribal populations, with a common origin in the last few millennia. In contrast, the Riang (Tibeto-Burman-speaking) and Andamanese have their nearest neighbour lineages in East Asia. The Jarawa and Onge shared haplogroup D lineages with each other within the last ~7000 years, but had diverged from Japanese haplogroup D Y-chromosomes ~53000 years ago, most likely by a split from a shared ancestral population. This analysis suggests that Indian populations have complex ancestry which cannot be explained by a single expansion model.
• dc.description.sponsorship Funding was provided by the joint Spain–India bilateral grant PRI-PIBIN-2011-0942 and BFU2016-77961-P (AEI/ FEDER, UE) both awarded by the Ministerio de Economía y Competitividad (Spain) and with the support of Secretaria d’Universitats i Recerca del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2014 SGR 866). Anders Bergström, YaliXue and Chris Tyler-Smith were supported by The Wellcome Trust (Grant 098051)
• dc.format.mimetype application/pdf
• dc.identifier.citation Mondal M, Bergström A, Xue Y, Calafell F, Laayouni H, Casals F et al. Y-chromosomal sequences of diverse Indian populations and the ancestry of the Andamanese. Hum Genet. 2017 May;136(5):499-510. DOI: 10.1007/s00439-017-1800-0
• dc.identifier.doi http://dx.doi.org/10.1007/s00439-017-1800-0
• dc.identifier.issn 0340-6717
• dc.identifier.uri http://hdl.handle.net/10230/34399
• dc.language.iso eng
• dc.publisher Springerca
• dc.relation.ispartof Human Genetics. 2017 May;136(5):499-510
• dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2016-77961-P
• dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s00439-017-1800-0
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.other Cromosomes humans
• dc.subject.other Cromosoma Y
• dc.subject.other Genètica de poblacions
• dc.subject.other ADN -- Anàlisi
• dc.title Y-chromosomal sequences of diverse Indian populations and the ancestry of the Andamaneseca
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion