Validation of the spanish version of the PURE-4 questionnaire for the early detection of psoriatic arthritis in psoriatic patients

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  • dc.contributor.author Belinchón Romero, Isabel
  • dc.contributor.author López-Ferrer, Anna
  • dc.contributor.author Ferran Farrés, Marta
  • dc.contributor.author Rivera Díaz, Raquel
  • dc.contributor.author Vidal Sarró, David
  • dc.contributor.author Rodríguez Fernández-Freire, Lourdes
  • dc.contributor.author Cueva, Pablo de la
  • dc.contributor.author Santos-Juanes, Jorge
  • dc.contributor.author Rocamora Durán, Vicenç
  • dc.contributor.author Martín Vázquez, Víctor
  • dc.contributor.author Gómez Labrador, Lara
  • dc.contributor.author Queiro Silva, Ruben
  • dc.contributor.author PURE-4 Study Group
  • dc.date.accessioned 2024-12-09T07:19:48Z
  • dc.date.available 2024-12-09T07:19:48Z
  • dc.date.issued 2024
  • dc.description Article disponible en castellà: http://hdl.handle.net/10230/68938
  • dc.description.abstract Background and objective: Psoriasis often precedes the onset of psoriatic arthritis (PsA), so dermatologists often face the challenge of early identifying signs of PsA in patients with psoriasis. Our aim was to validate the Spanish version of the PURE-4 questionnaire as a screening tool for PsA, evaluate its performance in terms of sensitivity, specificity, feasibility, reliability, and build validity. Methods: This was a cross-sectional, observational, multicenter trial of adult patients with psoriasis. Initially, patients were assessed by a dermatologist and completed 2 self-administered versions (in print and online) of the PURE-4 questionnaire. Afterwards, the rheumatologist, blinded to the PURE-4 results, assessed the presence/absence of PsA, being the reference to determine the performance of the PURE-4 questionnaire. Results: A total of 268 patients were included (115 [42.9%] women; mean age, 47.1±12.6). The prevalence of PsA according to rheumatologist diagnosis was 12.7% (34 patients). The mean PURE-4 score for patients with psoriasis diagnosed with PsA was 2.3±1.1, and 1.3±1.3 for patients without PsA (P<.001). The cutoff value ≥2 demonstrated the best performance for detecting PsA, with a negative predictive value of 95.1% (95% confidence interval, 90.3-97.6). Conclusions: The PURE-4 questionnaire demonstrated good performance in detecting PsA, with an optimal cutoff point ≥2. This simple tool could facilitate early referral of patients to the rheumatology unit.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Belinchón-Romero I, López-Ferrer A, Ferrán i Farrés M, Rivera-Díaz R, Vidal-Sarro D, Fernández-Freire R, et al. Validation of the spanish version of the PURE-4 questionnaire for the early detection of psoriatic arthritis in psoriatic patients. Actas Dermosifiliogr. 2024 Jul-Aug;115(7):T654-T662. DOI: 10.1016/j.ad.2024.05.010
  • dc.identifier.doi http://dx.doi.org/10.1016/j.ad.2024.05.010
  • dc.identifier.issn 0001-7310
  • dc.identifier.uri http://hdl.handle.net/10230/68937
  • dc.language.iso eng
  • dc.publisher Elsevier
  • dc.relation.ispartof Actas Dermosifiliogr. 2024 Jul-Aug;115(7):T654-T662
  • dc.rights © 2024 AEDV. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
  • dc.subject.keyword Psoriasis
  • dc.subject.keyword Psoriatic arthritis
  • dc.subject.keyword Screening
  • dc.subject.keyword PURE-4
  • dc.subject.keyword Referral
  • dc.subject.keyword Diagnostic performance
  • dc.title Validation of the spanish version of the PURE-4 questionnaire for the early detection of psoriatic arthritis in psoriatic patients
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion