Study of risk factors for healthcare-associated infections in acute cardiac patients using categorical principal component analysis (CATPCA)
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- dc.contributor.author Renes Carreño, Emilio
- dc.contributor.author Escribá Bárcena, Almudena
- dc.contributor.author Catalán González, Mercedes
- dc.contributor.author Álvarez Lerma, Francisco
- dc.contributor.author Palomar Martínez, Mercedes
- dc.contributor.author Nuvials Casals, Xavier
- dc.contributor.author Jaén Herreros, Felisa
- dc.contributor.author Montejo González, Juan Carlos
- dc.date.accessioned 2022-10-21T06:25:54Z
- dc.date.available 2022-10-21T06:25:54Z
- dc.date.issued 2022
- dc.description.abstract Using categorical principal component analysis, we aimed to determine the relationship between health care-associated infections (HAIs) and diagnostic categories (DCs) in patients with acute heart disease using data collected in the Spanish prospective ENVIN-HELICS intensive care registry over a 10-year period (2005-2015). A total of 69,876 admissions were included, of which 5597 developed HAIs. Two 2-component CATPCA models were developed. In the first model, all cases were included; the first component was determined by the duration of the invasive devices, the ICU stay, the APACHE II score and the HAIs; the second component was determined by the type of admission (medical or surgical) and by the DCs. No clear association between DCs and HAIs was found. Cronbach's alpha was 0.899, and the variance accounted for (VAF) was 52.5%. The second model included only admissions that developed HAIs; the first component was determined by the duration of the invasive devices and the ICU stay; the second component was determined by the inflammatory response, the mortality in the ICU and the HAIs. Cronbach's alpha value was 0.855, and VAF was 46.9%. These findings highlight the role of exposure to invasive devices in the development of HAIS in patients with acute heart disease.
- dc.format.mimetype application/pdf
- dc.identifier.citation Renes Carreño E, Escribá Bárcena A, Catalán González M, Álvarez Lerma F, Palomar Martínez M, Nuvials Casals X, Jaén Herreros F, Montejo González JC. Study of risk factors for healthcare-associated infections in acute cardiac patients using categorical principal component analysis (CATPCA). Sci Rep. 2022 Jan 7;12(1):28. DOI: 10.1038/s41598-021-03970-w
- dc.identifier.doi http://dx.doi.org/10.17235/reed.2022.8409/2021
- dc.identifier.issn 2045-2322
- dc.identifier.uri http://hdl.handle.net/10230/54521
- dc.language.iso eng
- dc.publisher Nature Research
- dc.relation.ispartof Rev Esp Enferm Dig. 2022 Mar 14
- dc.rights © The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Epidemiology
- dc.subject.keyword Preventive medicine
- dc.title Study of risk factors for healthcare-associated infections in acute cardiac patients using categorical principal component analysis (CATPCA)
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion