Databases and resources for human small non-coding RNAs
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- dc.contributor.author Agirre Ortiz de Guzmán, Eneritz, 1983-ca
- dc.contributor.author Eyras Jiménez, Eduardoca
- dc.date.accessioned 2015-12-18T15:16:52Z
- dc.date.available 2015-12-18T15:16:52Z
- dc.date.issued 2011
- dc.description.abstract Recent advances in high-throughput sequencing have facilitated the genome-wide studies of small non-coding RNAs (sRNAs). Numerous studies have highlighted the role of various classes of sRNAs at different levels of gene regulation and disease. The fast growth of sequence data and the diversity of sRNA species have prompted the need to organise them in annotation databases. There are currently several databases that collect sRNA data. Various tools are provided for access, with special emphasis on the well-characterised family of micro-RNAs. The striking heterogeneity of the new classes of sRNAs and the lack of sufficient functional annotation, however, make integration of these datasets a difficult task. This review describes the currently available databases for human sRNAs that are accessible via the internet, and some of the large datasets for human sRNAs from high-throughput sequencing experiments that are so far only available as supplementary data in publications. Some of the main issues related to the integration and annotation of sRNA datasets are also discussed.ca
- dc.format.mimetype application/pdfca
- dc.identifier.citation Agirre E, Eyras E. Databases and resources for human small non-coding RNAs. Human Genomics. 2011;5(3):192-9. DOI 10.1186/1479-7364-5-3-192ca
- dc.identifier.doi http://dx.doi.org/10.1186/1479-7364-5-3-192
- dc.identifier.issn 1479-7364
- dc.identifier.uri http://hdl.handle.net/10230/25476
- dc.language.iso engca
- dc.publisher BioMed Centralca
- dc.relation.ispartof Human Genomics. 2011;5(3):192-9
- dc.rights © 2011 Henry Stewart Publications. This is an Open Access article distributed under the terms of a Creative Commons Attribution Licenseca
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.subject.keyword MiRNAs
- dc.subject.keyword Small RNAs
- dc.subject.keyword Non-coding RNAs
- dc.subject.keyword High-throughput sequencing
- dc.subject.keyword Databases
- dc.subject.other RNAca
- dc.subject.other Bases de dadesca
- dc.subject.other Biologia computacionalca
- dc.title Databases and resources for human small non-coding RNAsca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersionca