The novel evolution of the sperm whale genome
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- dc.contributor.author Warren, Wesley C.ca
- dc.contributor.author Kuderna, Lukas, 1989-ca
- dc.contributor.author Alexander, Alanaca
- dc.contributor.author Catchen, Julianca
- dc.contributor.author Pérez Silva, José G.ca
- dc.contributor.author López Otín, Carlosca
- dc.contributor.author Quesada, Víctorca
- dc.contributor.author Minx, Patrickca
- dc.contributor.author Tomlinson, Chadca
- dc.contributor.author Montague, Michael J.ca
- dc.contributor.author Farias, Fabianaca
- dc.contributor.author Walter, Ronald B.ca
- dc.contributor.author Marquès i Bonet, Tomàs, 1975-ca
- dc.contributor.author Glenn, Travisca
- dc.contributor.author Kieran, Troy Johnca
- dc.contributor.author Wise, Sandra S.ca
- dc.contributor.author Wise, John Pierceca
- dc.contributor.author Waterhouse, Robert M.ca
- dc.date.accessioned 2018-04-05T07:45:32Z
- dc.date.available 2018-04-05T07:45:32Z
- dc.date.issued 2017
- dc.description.abstract The sperm whale, made famous by Moby Dick, is one of the most fascinating of all ocean-dwelling species given their unique life history, novel physiological adaptations to hunting squid at extreme ocean depths, and their position as one of the earliest branching toothed whales (Odontoceti). We assembled the sperm whale (Physeter macrocephalus) genome and resequenced individuals from multiple ocean basins to identify new candidate genes for adaptation to an aquatic environment and infer demographic history. Genes crucial for skin integrity appeared to be particularly important in both the sperm whale and other cetaceans. We also find sperm whales experienced a steep population decline during the early Pleistocene epoch. These genomic data add new comparative insight into the evolution of whales.
- dc.description.sponsorship This work was supported by the National Institute of Health grant 2R24OD011198-04A1 (W.C.W., PI); National Institute of Environmental Health Sciences [ES016893 (J.W. Sr, PI)]; Army Research Office [W911NF-09-1-0296 (J.W. Sr, PI)]; Swiss National Science Foundation grant PP00P3_170664 (R.M.W.); Ministerio of Economia and Competitividad (Spain); and European Union (ERC-Advanced Grant DeAge) (C.L.-O., PI); the Campbell Foundation; the Ocean Foundation; Ocean Alliance; and the many individual and anonymous Wise Laboratory donors. Work was conducted under National Marine Fisheries Service permit #1008-1637-03 (J.W. Sr, PI) and permit #751-1614 (I.K., PI). We thank Kyung Kim for computational support.
- dc.format.mimetype application/pdf
- dc.identifier.citation Warren WC, Kuderna L, Alexander A, Catchen J, Pérez-Silva JG, López-Otín C et al. The Novel Evolution of the Sperm Whale Genome. Genome Biol Evol. 2017 Dec 1;9(12):3260-4. DOI: 10.1093/gbe/evx187
- dc.identifier.doi http://dx.doi.org/10.1093/gbe/evx187
- dc.identifier.issn 1759-6653
- dc.identifier.uri http://hdl.handle.net/10230/34291
- dc.language.iso eng
- dc.publisher Oxford University Pressca
- dc.relation.ispartof Genome Biology and Evolution. 2017 Dec 1;9(12):3260-4
- dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/742067
- dc.rights © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
- dc.subject.keyword Sperm whale genome
- dc.subject.keyword Cetaceans
- dc.title The novel evolution of the sperm whale genomeca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion