Cost-effectiveness of strategies to increase screening coverage for cervical cancer in Spain: the CRIVERVA study

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  • dc.contributor.author Trapero-Bertran, Marta
  • dc.contributor.author Acera, Amelia
  • dc.contributor.author de Sanjosé, Silvia
  • dc.contributor.author Manresa, Josep Maria
  • dc.contributor.author Rodríguez, Diego
  • dc.contributor.author Rodriguez, Ana
  • dc.contributor.author Bonet, Josep Maria
  • dc.contributor.author Sanchez, Norman
  • dc.contributor.author Hidalgo, Pablo
  • dc.contributor.author Díaz Sanchis, Mireia
  • dc.date.accessioned 2025-01-20T07:32:58Z
  • dc.date.available 2025-01-20T07:32:58Z
  • dc.date.issued 2017
  • dc.description.abstract Background. The aim of the study is to carry out a cost-effectiveness analysis of three different interventions to promote the uptake of screening for cervical cancer in general practice in the county of Valles Occidental, Barcelona, Spain. Methods. Women aged from 30 to 70 years (n = 15,965) were asked to attend a general practice to be screened. They were randomly allocated to one of four groups: no intervention group (NIG); one group where women received an invitation letter to participate in the screening (IG1); one group where women received an invitation letter and informative leaflet (IG2); and one group where women received an invitation letter, an informative leaflet and a phone call reminder (IG3). Clinical effectiveness was measured as the percentage increase in screening coverage. A cost-effectiveness analysis was performed from the perspective of the public health system with a time horizon of three to five years – the duration of the randomised controlled clinical trial. In addition, a deterministic sensitivity analysis was performed. Results are presented according to different age groups. Results. The incremental cost-effectiveness ratio (ICER) for the most cost-effective intervention, IG1, compared with opportunistic screening was € 2.78 per 1% increase in the screening coverage. The age interval with the worst results in terms of efficiency was women aged < 40 years. Conclusions. In a population like Catalonia, with around 2 million women aged 30 to 70 years and assuming that 40% of these women were not attending general practice to be screened for cervical cancer, the implementation of an intervention to increase screening coverage which consists of sending a letter would cost on average less than € 490 for every 1000 women.en
  • dc.description.sponsorship This project was financed by the Spanish Ministry of Health (ISCIII Exp. PI10/01275) in the 2010 grant call of the Strategic Health Action Plan within the framework of the National Plan for Scientific Research, Development, and Innovative Technology. It was co-financed by the European Union through European Funds for Regional Development (FEDER). Partial support for the development of this work was received from Spanish public grants from the Instituto de Salud Carlos III (RTIC RD06/0020/0095, RD12/0036/0056, and CIBERESP) and from the Agència de Gestió d’Ajuts Universitaris i de Recerca (grants AGAUR 2014SGR1077 and 2014SGR2016). MD and SdS were partially supported by grants from the Spanish Government via the Instituto de Salud Carlos III-ISCIII cofunded by FEDER funds/European Regional Development Fund (ERDF)-a way to build Europe [PI11/02090, PI14/01219, PI16/01254, CIBERESP CB06/02/0073 and CB16/12/00401, and the Spanish Cancer Network RTICC RD12/0036/0056], the European Commission via the 7th Framework Program [CoheaHr Project 603019], the Government of Catalonia via the Agència de Gestió d'Ajuts Universitaris i de Recerca [2014SGR1077 and 2014SGR756] and from Recercaixa [MD088652].en
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Trapero-Bertran M, Acera A, de Sanjosé S, Manresa JM, Rodríguez D, Rodriguez Martinez A, et al. Cost-effectiveness of strategies to increase screening coverage for cervical cancer in Spain: the CRIVERVA study. BMC Public Health. 2017 Dec;17(1):194. DOI: 10.1186/s12889-017-4115-0
  • dc.identifier.doi http://dx.doi.org/10.1186/s12889-017-4115-0
  • dc.identifier.issn 1471-2458
  • dc.identifier.uri http://hdl.handle.net/10230/69177
  • dc.language.iso eng
  • dc.publisher BioMed Central
  • dc.relation.ispartof BMC Public Health. 2017 Dec;17(1):194
  • dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/603019
  • dc.rights © [Author(s)]. Creative Commons Attribution License http://creativecommons.org/licenses/by/2.0/
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/2.0/
  • dc.subject.keyword Cost-effectivenessen
  • dc.subject.keyword Population screeningen
  • dc.subject.keyword Cervical canceren
  • dc.subject.keyword Increase coverageen
  • dc.title Cost-effectiveness of strategies to increase screening coverage for cervical cancer in Spain: the CRIVERVA studyen
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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