Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgery
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author Climent Biescas, Elisendaca
- dc.contributor.author Benaiges Foix, Davidca
- dc.contributor.author Pedro-Botet, Juan Carlosca
- dc.contributor.author Flores-Le-Roux, Juana Antoniaca
- dc.contributor.author Ramón Moros, José Manuelca
- dc.contributor.author Villatoro Moreno, Montserratca
- dc.contributor.author Fontane Francia, Laiaca
- dc.contributor.author Chillarón Jordan, Juan Joséca
- dc.contributor.author Goday Arno, Albertoca
- dc.date.accessioned 2018-02-07T08:15:38Z
- dc.date.issued 2017
- dc.description.abstract PURPOSE: Given the lack of evidence of the effect of bariatric surgery (BS) on atherogenic dyslipidemia (AD), which is a characteristic of obese subjects, this study aimed to describe the remission rate of AD 1 year after BS in severely obese patients. MATERIALS AND METHODS: A non-randomised, prospective cohort study was conducted in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy with a 1-year follow-up. AD was defined as triglycerides ≥1.71 mmol/l or treatment with fibrates and low high-density lipoprotein (HDL) cholesterol (<1.03 mmol/l in men or <1.3 mmol/l in women). RESULTS: AD was present in 81 (22.8%) of the 356 patients; these were more frequently men and presented higher total cholesterol and non-HDL cholesterol concentrations. AD remission rate was 74.1% at 3 months, 90.1% at 6 months and 96.3% at 12 months, respectively, after BS. In this group of patients, HDL cholesterol levels rose progressively (1.0 ± 0.2 to 1.5 ± 0.3 mmol/l, p < 0.001) and triglycerides decreased (2.5 ± 0.9 to 1.2 ± 0.5 mmol/l, p < 0.001) during follow-up. Regarding previous lipid-lowering therapy, fibrates and ezetimibe were withdrawn in all patients and statins in 69.4% 1 year after surgery. CONCLUSION: BS has beneficial effects on lipid profile, achieving complete remission of AD at 1 year of follow-up in almost all patients.
- dc.format.mimetype application/pdf
- dc.identifier.citation Climent E, Benaiges D, Pedro-Botet J, Flores-Le Roux JA, Ramón JM, Villatoro M. et al. Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgery. Obes Surg. 2017 Jun;27(6):1548-1553. DOI: 10.1007/s11695-016-2504-6
- dc.identifier.doi http://dx.doi.org/10.1007/s11695-016-2504-6
- dc.identifier.issn 0960-8923
- dc.identifier.uri http://hdl.handle.net/10230/33818
- dc.language.iso eng
- dc.publisher Springerca
- dc.relation.ispartof Obesity Surgery. 2017 Jun;27(6):1548-53
- dc.rights © Springer The final publication is available at Springer via http://dx.doi.org/10.1007/s11695-016-2504-6
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Atherogenic dyslipidemia
- dc.subject.keyword Atherogenic index
- dc.subject.keyword Bariatric surgery
- dc.subject.other Obesitat mòrbida
- dc.subject.other Obesitat -- Cirurgia
- dc.title Atherogenic Dyslipidemia Remission 1 Year After Bariatric Surgeryca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion