Pityriasis rubra pilaris: a multicentric case series of 65 spanish patients

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  • dc.contributor.author Montero Menárguez, Julia
  • dc.contributor.author Amat Samaranch, Victoria
  • dc.contributor.author Puig Sanz, Lluís
  • dc.contributor.author Ruiz Villaverde, Ricardo
  • dc.contributor.author Arias Santiago, Salvador
  • dc.contributor.author Larrea García, Mónica
  • dc.contributor.author Ruiz Genao, Diana
  • dc.contributor.author Ferran Farrés, Marta
  • dc.contributor.author Schneller-Pavelescu, Luca
  • dc.contributor.author Romero Ferreiro, Carmen
  • dc.contributor.author Rivera Díaz, Raquel
  • dc.date.accessioned 2024-09-26T06:19:24Z
  • dc.date.available 2024-09-26T06:19:24Z
  • dc.date.issued 2024
  • dc.description Article disponible en castellà: http://hdl.handle.net/10230/61229
  • dc.description.abstract Introduction: PRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians. Objective: To add our experience to increase evidence about PRP. Methods: We performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP. Results: PRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years). Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response. Conclusion: Our study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Montero-Menárguez J, Amat Samaranch V, Puig Sanz L, Ruiz-Villaverde R, Arias-Santiago S, Larrea García M, et al. Pityriasis rubra pilaris: a multicentric case series of 65 spanish patients. Actas Dermosifiliogr. 2024 Sep;115(8):t761-t5. DOI: 10.1016/j.ad.2024.02.019
  • dc.identifier.doi http://dx.doi.org/10.1016/j.ad.2024.02.019
  • dc.identifier.issn 0001-7310
  • dc.identifier.uri http://hdl.handle.net/10230/61230
  • dc.language.iso eng
  • dc.publisher Elsevier
  • dc.relation.ispartof Actas Dermosifiliogr. 2024 Sep;115(8):t761-t5
  • dc.rights © 2024 AEDV. Published by Elsevier España, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
  • dc.subject.keyword Pityriasis rubra pilaris
  • dc.subject.keyword Biologic agents
  • dc.subject.keyword Erythroderma
  • dc.title Pityriasis rubra pilaris: a multicentric case series of 65 spanish patients
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion