Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription
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- dc.contributor.author Nadal Clanchet, Eulàlia deca
- dc.contributor.author Posas Garriga, Francescca
- dc.date.accessioned 2016-02-01T17:46:11Z
- dc.date.available 2016-02-01T17:46:11Z
- dc.date.issued 2015
- dc.description.abstract Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology change during adaptation. Major changes in gene expression are associated with cell exposure to environmental changes, and several aspects of mRNA biogenesis appear to be targeted by signaling pathways upon stress. Exhaustive reviews have been written regarding adaptation to stress and regulation of gene expression. In this review, using osmostress in yeast as a prototypical case study, we highlight those aspects of regulation of gene induction that are general to various environmental stresses as well as mechanistic aspects that are potentially conserved from yeast to mammals.ca
- dc.description.sponsorship The laboratory of F.P. and E.N. is supported by grants from the Spanish Ministry of Economy and Competitiveness (BFU2012-33503 and FEDER, BFU2014-52125-REDT and BFU2014-51672-REDC to F.P. and BFU2014-52333-P to E.N.), the Catalan Government (2014 SGR 599) and an ERC Advanced Grant (number 294294) from the EU seventh framework program (SYNCOM) to F.P. This project is supported by the Fundación Botín and by Banco Santander through its Santander Universities Global Division to F.P. F.P. and E.N. are recipients of an ICREA Acadèmia (Generalitat de Catalunya).
- dc.format.mimetype application/pdfca
- dc.identifier.citation de Nadal E, Posas F. Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription. FEBS Journal. 2015; 282(17): 3275-3285. DOI 10.1111/febs.13323ca
- dc.identifier.doi http://dx.doi.org/10.1111/febs.13323
- dc.identifier.issn 1742-464X
- dc.identifier.uri http://hdl.handle.net/10230/25711
- dc.language.iso engca
- dc.publisher Wileyca
- dc.relation.ispartof FEBS Journal. 2015; 282(17): 3275-3285
- dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/294294
- dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BFU2012-33503
- dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2014-52125-REDT
- dc.relation.projectID info:eu-repo/grantAgreement/ES/1PE/BFU2014-51672-REDC
- dc.relation.projectID info:eu‐repo/grantAgreement/ES/1PE/BFU2014-52333-P
- dc.rights © 2015 The Authors. FEBS Journal published by John Wiley & Sons Ltd on behalf of FEBS. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.ca
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ca
- dc.subject.keyword Gene expression
- dc.subject.keyword Hog1
- dc.subject.keyword Mammals
- dc.subject.keyword Osmostress
- dc.subject.keyword p38
- dc.subject.keyword SAPK
- dc.subject.keyword Stress responses
- dc.subject.keyword Yeast
- dc.subject.other Cèl·lulesca
- dc.subject.other Proteïnes quinasesca
- dc.title Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcriptionca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersionca