Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypes

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  • dc.contributor.author Ferreira, Pedro G.ca
  • dc.contributor.author Patalano, Solennca
  • dc.contributor.author Chauhan, Ritikaca
  • dc.contributor.author Ffrench-Constant, Richardca
  • dc.contributor.author Gabaldón Estevan, Juan Antonio, 1973-ca
  • dc.contributor.author Guigó Serra, Rodericca
  • dc.contributor.author Sumner, Seirianca
  • dc.date.accessioned 2014-05-12T13:19:08Z
  • dc.date.available 2014-05-12T13:19:08Z
  • dc.date.issued 2013ca
  • dc.description.abstract BACKGROUND: Understanding how alternative phenotypes arise from the same genome is a major challenge in modern biology. Eusociality in insects requires the evolution of two alternative phenotypes - workers, who sacrifice personal reproduction, and queens, who realize that reproduction. Extensive work on honeybees and ants has revealed the molecular basis of derived queen and worker phenotypes in highly eusocial lineages, but we lack equivalent deep-level analyses of wasps and of primitively eusocial species, the latter of which can reveal how phenotypic decoupling first occurs in the early stages of eusocial evolution. RESULTS: We sequenced 20 Gbp of transcriptomes derived from brains of different behavioral castes of the primitively eusocial tropical paper wasp Polistes canadensis. Surprisingly, 75% of the 2,442 genes differentially expressed between phenotypes were novel, having no significant homology with described sequences. Moreover, 90% of these novel genes were significantly upregulated in workers relative to queens. Differential expression of novel genes in the early stages of sociality may be important in facilitating the evolution of worker behavioral complexity in eusocial evolution. We also found surprisingly low correlation in the identity and direction of expression of differentially expressed genes across similar phenotypes in different social lineages, supporting the idea that social evolution in different lineages requires substantial de novo rewiring of molecular pathways. CONCLUSIONS: These genomic resources for aculeate wasps and first transcriptome-wide insights into the origin of castes bring us closer to a more general understanding of eusocial evolution and how phenotypic diversity arises from the same genome.
  • dc.description.sponsorship This work was supported by RCUK, CONSOLIDER (CSD2007-0005), the Spanish Ministry of Science/n(BIO2006-03380, BFU2009-09168), GTEX (NIH Project 1RO1MH090941-01), a UK Research Council (RCUK) fellowship, and PGF by a FCT postdoctoral grant (SFRH/BPD/42003/2007) from the Portuguese Ministry of Science and Technology. The fieldwork was/nconducted under ANAM Permit No. SE/A-33-09
  • dc.format.mimetype application/pdfca
  • dc.identifier.citation Ferreira PG, Patalano S, Chauhan R, Ffrench-Constant R, Gabaldón T, Guigó R et al. Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypes. Genome Biol. 2013;14(2):R20. DOI: 10.1186/gb-2013-14-2-r20ca
  • dc.identifier.doi http://dx.doi.org/10.1186/gb-2013-14-2-r20
  • dc.identifier.issn 1465-6906ca
  • dc.identifier.uri http://hdl.handle.net/10230/22478
  • dc.language.iso engca
  • dc.publisher BioMed Centralca
  • dc.relation.ispartof Genome biology. 2013;14(2):R20
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/2PN/BIO2006-03380
  • dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BFU2009-09168
  • dc.rights © 2013 Pedro G. Ferreira et al. This article is distributed under a Creative Commons Attribution Licenseca
  • dc.rights.accessRights info:eu-repo/semantics/openAccessca
  • dc.rights.uri http://creativecommons.org/licenses/by/2.0/
  • dc.subject.other Genòmica
  • dc.subject.other Fenotip
  • dc.title Transcriptome analyses of primitively eusocial wasps reveal novel insights into the evolution of sociality and the origin of alternative phenotypesca
  • dc.type info:eu-repo/semantics/articleca
  • dc.type.version info:eu-repo/semantics/publishedVersionca

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Articles (Center for Genomic Regulation (CRG))
Articles (Departament de Medicina i Ciències de la Vida)