Obstetric outcomes of SARS-CoV-2 infection in asymptomatic pregnant women
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- dc.contributor.author Cruz-Lemini, Mónica
- dc.contributor.author Ferriols Pérez, Elena
- dc.contributor.author Espuelas Malón, Silvia
- dc.contributor.author Martínez Pérez, Oscar
- dc.contributor.author Spanish Obstetric Emergency Group
- dc.date.accessioned 2022-02-25T07:37:54Z
- dc.date.available 2022-02-25T07:37:54Z
- dc.date.issued 2021
- dc.description.abstract Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms.
- dc.format.mimetype application/pdf
- dc.identifier.citation Cruz-Lemini M, Ferriols Perez E, de la Cruz Conty ML, Caño Aguilar A, Encinas Pardilla MB, Prats Rodríguez P, et al. Obstetric outcomes of SARS-CoV-2 infection in asymptomatic pregnant women. Viruses. 2021 Jan 15; 13(1): 112. DOI: 10.3390/v13010112
- dc.identifier.doi http://dx.doi.org/10.3390/v13010112
- dc.identifier.issn 1999-4915
- dc.identifier.uri http://hdl.handle.net/10230/52578
- dc.language.iso eng
- dc.publisher MDPI
- dc.rights Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword SARS-CoV-2
- dc.subject.keyword Asymptomatic infection
- dc.subject.keyword Coronavirus
- dc.subject.keyword Delivery
- dc.subject.keyword Maternal complications
- dc.subject.keyword Perinatal outcomes
- dc.subject.keyword Pregnancy
- dc.title Obstetric outcomes of SARS-CoV-2 infection in asymptomatic pregnant women
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion