Substance use disorders and cooperative research on addictions: Spanish approach as a model
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- dc.contributor.author Cárdenas Quesada, Jose
- dc.contributor.author Mestre-Pintó, Juan Ignacio
- dc.contributor.author Maldonado, Rafael, 1961-
- dc.contributor.author Rodríguez de Fonseca, Fernando
- dc.contributor.author Torrens, Marta
- dc.contributor.author Farré Albaladejo, Magí
- dc.date.accessioned 2024-07-18T06:56:27Z
- dc.date.available 2024-07-18T06:56:27Z
- dc.date.issued 2024
- dc.description.abstract Substance use disorders (SUD), also named addiction when it is severe, is a chronic brain disorder with serious impact on individual who suffer, the public health and with high burden of disease. They are multitude of mechanisms/factors involved in addiction: from individual characteristics of the person (from genetic to impacts of stress, sex, and age) to social and environmental situation (availability and accessibility of substances, cultural and legal aspects, socio-economical situation) and type of substance of use (pharmacological characteristics) Then, research on Addiction must include different, complementary, and translational perspectives. In this review, we explore the neurobiological, psychosocial, and epidemiological knowledge of substance addiction, and the main role played by pharmacology in the research in this field. In Spain, since 2002, collaborative networks have emerged for comprehensive research on addictions, with the creation of the Addictive Disorders Network (RTA), currently redefined as the Research Network for Primary Care in Addictions (RIAPAd) with the support of the Carlos III Health Institute (Instituto de Salud Carlos III). Basic (including neuropharmacology and behavioral pharmacology), clinical and epidemiological research groups stand out, combining efforts to address prevention, early detection and treatment through interdisciplinary cooperation and the subsequent dissemination of results.
- dc.format.mimetype application/pdf
- dc.identifier.citation Cárdenas-Quesada J, Mestre-Pintó J, Maldonado R, Rodríguez de Fonseca F, Torrens M, Farré M. Substance use disorders and cooperative research on addictions: Spanish approach as a model. Pharmacol Res. 2024 Jun 2;206:107233. DOI: 10.1016/j.phrs.2024.107233
- dc.identifier.doi http://dx.doi.org/10.1016/j.phrs.2024.107233
- dc.identifier.issn 1043-6618
- dc.identifier.uri http://hdl.handle.net/10230/60776
- dc.language.iso eng
- dc.publisher Elsevier
- dc.relation.ispartof Pharmacol Res. 2024 Jun 2;206:107233
- dc.rights © 2024 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Addiction
- dc.subject.keyword Cooperative research
- dc.subject.keyword Epidemiology
- dc.subject.keyword Pharmacology
- dc.subject.keyword Substance use disorder
- dc.title Substance use disorders and cooperative research on addictions: Spanish approach as a model
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion