The 2023 MANCTRA acute biliary Pancreatitis care bundle: A joint effort between human knowledge and artificial intelligence (ChatGPT) to optimize the care of patients with acute biliary pancreatitis in western countries

Podda, Mauro; Di Martino, Marcello; Ielpo, Benedetto; Catena, Fausto; Coccolini, Federico; Pata, Francesco; Marchegiani, Giovanni; De Simone, Belinda; Damaskos, Dimitrios; Mole, Damian; Leppaniemi, Ari; Sartelli, Massimo; Baohong, Yang; Ansaloni, Luca; Biffl, Walter; Kluger, Yoram; Moore, Ernest E.; Pellino, Gianluca; Di Saverio, Salomone; Pisanu, Adolfo

The 2023 MANCTRA acute biliary Pancreatitis care bundle: A joint effort between human knowledge and artificial intelligence (ChatGPT) to optimize the care of patients with acute biliary pancreatitis in western countries

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dc.contributor.author Podda, Mauro
dc.contributor.author Di Martino, Marcello
dc.contributor.author Ielpo, Benedetto
dc.contributor.author Catena, Fausto
dc.contributor.author Coccolini, Federico
dc.contributor.author Pata, Francesco
dc.contributor.author Marchegiani, Giovanni
dc.contributor.author De Simone, Belinda
dc.contributor.author Damaskos, Dimitrios
dc.contributor.author Mole, Damian
dc.contributor.author Leppaniemi, Ari
dc.contributor.author Sartelli, Massimo
dc.contributor.author Baohong, Yang
dc.contributor.author Ansaloni, Luca
dc.contributor.author Biffl, Walter
dc.contributor.author Kluger, Yoram
dc.contributor.author Moore, Ernest E.
dc.contributor.author Pellino, Gianluca
dc.contributor.author Di Saverio, Salomone
dc.contributor.author Pisanu, Adolfo
dc.date.accessioned 2024-04-25T06:01:30Z
dc.date.available 2024-04-25T06:01:30Z
dc.date.issued 2024
dc.description.abstract Objective: To generate an up-to-date bundle to manage acute biliary pancreatitis using an evidence-based, artificial intelligence (AI)-assisted GRADE method. Background: A care bundle is a set of core elements of care that are distilled from the most solid evidence-based practice guidelines and recommendations. Methods: The research questions were addressed in this bundle following the PICO criteria. The working group summarized the effects of interventions with the strength of recommendation and quality of evidence applying the GRADE methodology. ChatGPT AI system was used to independently assess the quality of evidence of each element in the bundle, together with the strength of the recommendations. Results: The 7 elements of the bundle discourage antibiotic prophylaxis in patients with acute biliary pancreatitis, support the use of a full-solid diet in patients with mild to moderately severe acute biliary pancreatitis, and recommend early enteral nutrition in patients unable to feed by mouth. The bundle states that endoscopic retrograde cholangiopancreatography should be performed within the first 48 to 72 hours of hospital admission in patients with cholangitis. Early laparoscopic cholecystectomy should be performed in patients with mild acute biliary pancreatitis. When operative intervention is needed for necrotizing pancreatitis, this should start with the endoscopic step-up approach. Conclusions: We have developed a new care bundle with 7 key elements for managing patients with acute biliary pancreatitis. This new bundle, whose scientific strength has been increased thanks to the alliance between human knowledge and AI from the new ChatGPT software, should be introduced to emergency departments, wards, and intensive care units.
dc.format.mimetype application/pdf
dc.identifier.citation Podda M, Di Martino M, Ielpo B, Catena F, Coccolini F, Pata F, et al. The 2023 MANCTRA acute biliary Pancreatitis care bundle: A joint effort between human knowledge and artificial intelligence (ChatGPT) to optimize the care of patients with acute biliary pancreatitis in western countries. Ann Surg. 2024 Feb 1;279(2):203-12. DOI: 10.1097/SLA.0000000000006008
dc.identifier.doi http://dx.doi.org/10.1097/SLA.0000000000006008
dc.identifier.issn 0003-4932
dc.identifier.uri http://hdl.handle.net/10230/59902
dc.language.iso eng
dc.publisher Wolters Kluwer (LWW)
dc.relation.ispartof Ann Surg. 2024 Feb 1;279(2):203-12
dc.rights © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/
dc.rights.accessRights info:eu-repo/semantics/openAccess
dc.rights.uri http://creativecommons.org/licenses/by/4.0/
dc.subject.keyword Acute biliary pancreatitis
dc.subject.keyword Artificial intelligence
dc.subject.keyword Care bundle
dc.subject.keyword ChatGPT
dc.subject.keyword Clinical indicators
dc.subject.keyword GRADE
dc.subject.keyword Guidelines
dc.title The 2023 MANCTRA acute biliary Pancreatitis care bundle: A joint effort between human knowledge and artificial intelligence (ChatGPT) to optimize the care of patients with acute biliary pancreatitis in western countries
dc.type info:eu-repo/semantics/article
dc.type.version info:eu-repo/semantics/publishedVersion

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