Patch test results with the European baseline series, 2019/20-joint European results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC
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- dc.contributor.author Uter, Wolfgang
- dc.contributor.author Giménez Arnau, Anna Maria
- dc.contributor.author Gonçalo, Margarida
- dc.contributor.author GEIDAC
- dc.date.accessioned 2022-10-20T06:58:44Z
- dc.date.available 2022-10-20T06:58:44Z
- dc.date.issued 2022
- dc.description.abstract Background: continual analyses of patch test results with the European baseline series (EBS) serve both contact allergy surveillance and auditing the value of included allergens. Objectives: to present results of current EBS patch testing, obtained in 53 departments in 13 European countries during 2019 and 2020. Methods: Anonymised or pseudonymised individual data and partly aggregated data on demographic/clinical characteristics and patch test rest results with the EBS were prospectively collected and centrally pooled and analysed. Results: in 2019 and 2020, 22 581 patients were patch tested with the EBS. Sensitization to nickel remained most common (19.8 [19.2-20.4]% positivity [95% confidence interval]). Fragrance mix I and Myroxylon pereirae yielded very similar results with 6.80 (6.43-7.19)% and 6.62 (6.25-7.00)% positivity, respectively. Formaldehyde at 2% aq. yielded almost one percentage point more positive reactions than 1% concentration (2.49 [2.16-2.85]% vs. 1.59 [1.33-1.88]); methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI alone up to around 5% positives. Among the new additions, propolis was most commonly positive (3.48 [3.16-3.82]%), followed by 2-hydroxyethyl methacrylate (2.32 [2.0-2.68]%). Conclusion: ongoing surveillance on the prevalence of contact sensitization contributes to an up-to-date baseline series containing the most frequent and/or relevant contact sensitizers for routine patch testing in Europe.
- dc.format.mimetype application/pdf
- dc.identifier.citation Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, et al. Patch test results with the European baseline series, 2019/20-joint European results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC. Contact Dermatitis. 2022 Oct; 87(4): 343-55. DOI: 10.1111/cod.14170.
- dc.identifier.doi http://dx.doi.org/10.1111/cod.14170
- dc.identifier.issn 0105-1873
- dc.identifier.uri http://hdl.handle.net/10230/54499
- dc.language.iso eng
- dc.publisher Wiley
- dc.rights This is the peer reviewed version of the following article: Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, et al. Patch test results with the European baseline series, 2019/20-joint European results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC. Contact Dermatitis. 2022 Oct; 87(4): 343-55, which has been published in final form at http://dx.doi.org/10.1111/cod.14170. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword RRID
- dc.subject.keyword SCR_001905
- dc.subject.keyword baseline series
- dc.subject.keyword Clinical epidemiology
- dc.subject.keyword Contact allergy
- dc.subject.keyword Patch testing
- dc.subject.keyword Surveillance
- dc.title Patch test results with the European baseline series, 2019/20-joint European results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion