Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study

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• dc.contributor.author Bazal, P.
• dc.contributor.author Gea, Alfredo
• dc.contributor.author Martínez-González, Miguel Ángel, 1957-
• dc.contributor.author Salas-Salvadó, Jordi
• dc.contributor.author Asensio, Eva María
• dc.contributor.author Muñoz-Bravo, Carlos
• dc.contributor.author Fiol, Miquel
• dc.contributor.author Muñoz, Miguel Ángel
• dc.contributor.author Lapetra, José
• dc.contributor.author Serra-Majem, Luis
• dc.contributor.author Pinto, Xavier
• dc.contributor.author González, José I.
• dc.contributor.author Becerra-Tomás, Nerea
• dc.contributor.author Fitó Colomer, Montserrat
• dc.contributor.author Ros, Emilio
• dc.contributor.author Alonso-Gómez, Ángel
• dc.contributor.author Ruiz-Canela, Miguel
• dc.date.accessioned 2020-03-23T07:36:31Z
• dc.date.issued 2019
• dc.description.abstract Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP) (10-30 g/d in men and 5-15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67-1.37), adherents to MADP (HR: 1.15 95%CI: 0.75-1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53-1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption) was not associated with an increased incidence of AF.
• dc.format.mimetype application/pdf
• dc.identifier.citation Bazal P, Gea A, Martínez-González MA, Salas-Salvadó J, Asensio EM, Muñoz-Bravo C, et al. Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study. Nutr Metab Cardiovasc Dis. 2019 Jul; 29(7):676-83. DOI: 10.1016/j.numecd.2019.03.007
• dc.identifier.doi http://dx.doi.org/10.1016/j.numecd.2019.03.007
• dc.identifier.issn 0939-4753
• dc.identifier.uri http://hdl.handle.net/10230/43982
• dc.language.iso eng
• dc.publisher Elsevier
• dc.rights © Elsevier http://dx.doi.org/10.1016/j.numecd.2019.03.007
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Alcohol;
• dc.subject.keyword Antioxidant
• dc.subject.keyword Atrial fibrillation
• dc.subject.keyword Mediterranean
• dc.subject.keyword Red wine
• dc.title Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion