Foot and ankle infections: Debridement, early fixation and rifampicin provide earlier recovery of function and quality of life

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• dc.contributor.author Pérez-Prieto, Daniel
• dc.contributor.author Portillo, María Eugenia
• dc.contributor.author González-Lucena, Gemma
• dc.contributor.author Ginés-Cespedosa, Alberto
• dc.date.accessioned 2018-11-09T08:30:11Z
• dc.date.available 2018-11-09T08:30:11Z
• dc.date.issued 2019
• dc.description.abstract BACKGROUND: Infection after foot and ankle fractures is a major concern for orthopedic surgeons. It is widely believed that final osteosynthesis should be delayed until the infection is cured. However, there is no literature that supports this practice. In addition, the delay impairs patient function and quality of life (QoL). METHODS: In the present study, four cases of ankle infection treated with aggressive debridement, early fixation and antibiofilm antibiotics are described. It is thought that, like other implant related infections, ankle infections can be rapidly treated with the definitive fixation and by curing the infection to make for a fast recovery of QoL and function. RESULTS: The infections were caused by MSSA and Pseudomonas aeruginosa in case 1, MSSA in case 2 and MRSA as well as K. pneumonia in case 3. Case 4 was a culture negative infection. They were susceptible to antibiofilm antibiotics (the gram-negative bacilli susceptible to ciprofloxacin and the gram-positive cocci susceptible to rifampicin). Cases 1, 3 and 4 were treated with a tibio-talo-calcaneal arthrodesis and case 2 was treated with a de-rotational fibular osteotomy and a medial closing wedge supramalleolar osteotomy. All cases improved at a median time of 4 weeks in terms of quality of life (SF-36) and function (AOFAS). At 2-years follow-up, no recurrence of infection was observed in any of the cases. All the cases achieved fusion or osteotomy healing at final follow-up. CONCLUSIONS: Early fixation after debridement combined with antibiofilm antibiotics can be performed in foot and ankle inflections to provide early recovery of QoL and function in patients
• dc.format.mimetype application/pdf
• dc.identifier.citation Pérez-Prieto D, Portillo ME, González-Lucena G, Ginés-Cespedosa A. et al. Foot and ankle infections: Debridement, early fixation and rifampicin provide earlier recovery of function and quality of life. Foot Ankle Surg. 2019 Feb;25(1):13-18. DOI: 10.1016/j.fas.2017.07.644
• dc.identifier.doi http://dx.doi.org/10.1016/j.fas.2017.07.644
• dc.identifier.issn 1268-7731
• dc.identifier.uri http://hdl.handle.net/10230/35724
• dc.language.iso eng
• dc.publisher Elsevier
• dc.relation.ispartof Foot and Ankle Surgery. 2019 Feb;25(1):13-8
• dc.rights © Elsevier http://dx.doi.org/10.1016/j.fas.2017.07.644
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.subject.keyword Biofilm
• dc.subject.keyword Foot and ankle infection
• dc.subject.keyword Quality of life
• dc.subject.keyword Rifampicin
• dc.subject.other Peus -- Malalties
• dc.subject.other Fractures -- Infeccions
• dc.subject.other Qualitat de vida
• dc.title Foot and ankle infections: Debridement, early fixation and rifampicin provide earlier recovery of function and quality of life
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/acceptedVersion