Statins for primary cardiovascular prevention in the elderly
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- dc.contributor.author Pedro-Botet, Juan Carlosca
- dc.contributor.author Climent Biescas, Elisendaca
- dc.contributor.author Chillarón Jordan, Juan Joséca
- dc.contributor.author Toro, Rocioca
- dc.contributor.author Benaiges Foix, Davidca
- dc.contributor.author Flores-Le-Roux, Juana Antoniaca
- dc.date.accessioned 2016-02-22T09:01:13Z
- dc.date.available 2016-02-22T09:01:13Z
- dc.date.issued 2015
- dc.description.abstract The elderly population is increasing worldwide, with subjects > 65 years of age constituting the fastest-growing age group. Furthermore, the elderly face the greatest risk and burden of cardiovascular disease mortality and morbidity. Although elderly patients, particularly those older > 75, have not been well represented in randomized clinical trials evaluating lipid-lowering therapy, the available evidence supporting the use of statin therapy in primary prevention in older individuals is derived mainly from subgroup analyses and post-hoc data. On the other hand, elderly patients often have multiple co-morbidities that require a high number of concurrent medications; this may increase the risk for drug-drug interactions, thereby reducing the potential benefits of statin therapy. The aim of this review was to present the relevant literature regarding statin use in the elderly for their primary cardiovascular disease, with the associated risks and benefits of treatment.ca
- dc.format.mimetype application/pdfca
- dc.identifier.citation Pedro-Botet J, Climent E, Chillarón JJ, Toro R, Benaiges D, Flores-Le Roux JA. Statins for primary cardiovascular prevention in the elderly. J Geriatr Cardiol. 2015 Jul;12(4):431-8. doi: 10.11909/j.issn.1671-5411.2015.04.016.ca
- dc.identifier.doi http://dx.doi.org/10.11909/j.issn.1671-5411.2015.04.016
- dc.identifier.issn 1671-5411
- dc.identifier.uri http://hdl.handle.net/10230/25918
- dc.language.iso engca
- dc.publisher Institute of Geriatric Cardiology, Chinese PLA General Hospitalca
- dc.relation.ispartof Journal of Geriatric Cardiology. 2015 Jul;12(4):431-8
- dc.rights This is an open-access article distributed under the terms of thehttp://creativecommons.org/licenses/by-nc-sa/3.0/, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.ca
- dc.rights.accessRights info:eu-repo/semantics/openAccessca
- dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/ca
- dc.subject.other Sistema cardiovascular -- Malalties -- Prevencióca
- dc.subject.other Persones grans -- Malalties -- Prevencióca
- dc.subject.other Lípids -- Metabolismeca
- dc.title Statins for primary cardiovascular prevention in the elderlyca
- dc.type info:eu-repo/semantics/articleca
- dc.type.version info:eu-repo/semantics/publishedVersionca