Increased nucleus accumbens volume in first-episode psychosis
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- dc.contributor.author Forns-Nadal, Mireiaca
- dc.contributor.author Berge Baquero, Danielca
- dc.contributor.author Seme, Federicoca
- dc.contributor.author Mané Santacana, Annaca
- dc.contributor.author Igual, Lauraca
- dc.contributor.author Guinart, Danica
- dc.contributor.author Vilarroya, Óscarca
- dc.date.accessioned 2018-03-01T08:33:56Z
- dc.date.issued 2017
- dc.description.abstract Nucleus accumbens has been reported as a key structure in the neurobiology of schizophrenia. Studies analyzing structural abnormalities have shown conflicting results, possibly related to confounding factors. We investigated the nucleus accumbens volume using manual delimitation in first-episode psychosis (FEP) controlling for age, cannabis use and medication. Thirty-one FEP subjects who were naive or minimally exposed to antipsychotics and a control group were MRI scanned and clinically assessed from baseline to 6 months of follow-up. FEP showed increased relative and total accumbens volumes. Clinical correlations with negative symptoms, duration of untreated psychosis and cannabis use were not significant.
- dc.format.mimetype application/pdf
- dc.identifier.citation Forns-Nadal M, Bergé D, Sem F, Mané A, Igual L, Guinart D. et al. Increased nucleus accumbens volume in first-episode psychosis. Psychiatry Res. 2017 May 30;263:57-60. DOI: 10.1016/j.pscychresns.2017.03.007
- dc.identifier.doi http://dx.doi.org/10.1016/j.pscychresns.2017.03.007
- dc.identifier.issn 0165-1781
- dc.identifier.uri http://hdl.handle.net/10230/34021
- dc.language.iso eng
- dc.publisher Elsevierca
- dc.relation.ispartof Psychiatry Research. 2017 May 30;263:57-60
- dc.rights © Elsevier http://dx.doi.org/10.1016/j.pscychresns.2017.03.007
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Neuroimaging
- dc.subject.keyword Region of interest
- dc.subject.keyword Reward
- dc.subject.keyword Schizophrenia
- dc.subject.other Esquizofrènia
- dc.subject.other Psicosi
- dc.title Increased nucleus accumbens volume in first-episode psychosisca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion