Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status
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- dc.contributor.author Kim, Kyeezu
- dc.contributor.author Joyce, Brian T.
- dc.contributor.author Nannini, Drew R.
- dc.contributor.author Zheng, Yinan
- dc.contributor.author Gordon-Larsen, Penny
- dc.contributor.author Shikany, James M.
- dc.contributor.author Lloyd-Jones, Donald M.
- dc.contributor.author Hu, Ming
- dc.contributor.author Nieuwenhuijsen, Mark J.
- dc.contributor.author Vaughan, Douglas E.
- dc.contributor.author Zhang, Kai
- dc.contributor.author Hou, Lifang
- dc.date.accessioned 2023-11-27T07:14:05Z
- dc.date.available 2023-11-27T07:14:05Z
- dc.date.issued 2023
- dc.description.abstract Slower epigenetic aging is associated with exposure to green space (greenness); however, the longitudinal relationship has not been well studied, particularly in minority groups. We investigated the association between 20-year exposure to greenness [Normalized Difference Vegetation Index (NDVI)] and epigenetic aging in a large, biracial (Black/white), U.S. urban cohort. Using generalized estimating equations adjusted for individual and neighborhood socioeconomic characteristics, greater greenness was associated with slower epigenetic aging. Black participants had less surrounding greenness and an attenuated association between greenness and epigenetic aging [βNDVI5km: -0.80, 95% confidence interval (CI): -4.75, 3.13 versus βNDVI5km: -3.03, 95% CI: -5.63, -0.43 in white participants]. Participants in disadvantaged neighborhoods showed a stronger association between greenness and epigenetic aging (βNDVI5km: -3.36, 95% CI: -6.65, -0.08 versus βNDVI5km: -1.57, 95% CI: -4.12, 0.96 in less disadvantaged). In conclusion, we found a relationship between greenness and slower epigenetic aging, and different associations by social determinants of health such as race and neighborhood socioeconomic status.
- dc.format.mimetype application/pdf
- dc.identifier.citation Kim K, Joyce BT, Nannini DR, Zheng Y, Gordon-Larsen P, Shikany JM, Lloyd-Jones DM, Hu M, Nieuwenhuijsen MJ, Vaughan DE, Zhang K, Hou L. Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status. Sci Adv. 2023 Jun 28;9(26):eadf8140. DOI: 10.1126/sciadv.adf8140
- dc.identifier.doi http://dx.doi.org/10.1126/sciadv.adf8140
- dc.identifier.issn 2375-2548
- dc.identifier.uri http://hdl.handle.net/10230/58375
- dc.language.iso eng
- dc.publisher American Association for the Advancement of Science (AAAS)
- dc.relation.ispartof Sci Adv. 2023 Jun 28;9(26):eadf8140
- dc.rights Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.other Epigenètica
- dc.subject.other Vegetació urbana
- dc.title Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion