Lack of population differentiation patterns of previously identified putatively adaptive transposable element insertions at microgeographic scales

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• dc.contributor.author González, Josefaca
• dc.contributor.author Martínez, Joséca
• dc.contributor.author Makalowski, Wojciechca
• dc.date.accessioned 2015-11-20T10:04:01Z
• dc.date.available 2015-11-20T10:04:01Z
• dc.date.issued 2015ca
• dc.description.abstract Background. Transposable elements (TEs) play an important role in genome function and evolution. It has been shown that TEs are a considerable source of adaptive changes in the genome of Drosophila melanogaster. Specifically, footprints of selection at the DNA level, the presence of population differentiation patterns across environmental gradients, and detailed mechanistic and fitness analyses of a few candidate adaptive TEs pointed to the role of TEs in environmental adaptation. However, whether the population differentiation patterns observed at large geographic scales can be replicated at a microgeographic scale has never been assessed before./nResults. In this work, we explored the population patterns of putatively adaptive TEs at a micro-spatial scale level. We compared the frequencies of TEs, previously identified as putatively adaptive and putatively neutral, in populations collected in opposite slopes of the Evolution Canyon at Mt. Carmel in Israel separated by 200 m on average. However, the differentiation patterns previously observed across large geographic distances (2000–2200 km) were not replicated at the microscale level of the Evolution Canyon populations./nConclusion. TE insertions previously associated with D. melanogaster environmental adaptation at a macro scale level do not play such a role at the microscale level of the Evolution Canyon populations. However, these results do not exclude a role of TEs in microgeographic adaptation because the dataset analyzed in this work is restricted to TEs identified in a single North American strain and as such is highly biased and incomplete.
• dc.description.sponsorship This work was supported by grants from the European Commission (PCIG-GA-2011-293860) and from the Spanish Government (BFU-2011-24397) awarded to JG and by the Institute of Bioinformatics funds awarded to WM. We acknowledge support of the publication fee by the CSIC Open Access Publication Support Initiative through its Unit of Information Resources for Research (URICI).
• dc.format.mimetype application/pdfca
• dc.identifier.citation González J, Martínez J, Makalowski W. Lack of population differentiation patterns of previously identified putatively adaptive transposable element insertions at microgeographic scales. Biology Direct. 2015;10:50. DOI: 10.1186/s13062-015-0075-4ca
• dc.identifier.doi http://dx.doi.org/10.1186/s13062-015-0075-4
• dc.identifier.issn 1745-6150ca
• dc.identifier.uri http://hdl.handle.net/10230/25169
• dc.language.iso engca
• dc.publisher BioMed Centralca
• dc.relation.ispartof Biology Direct. 2015;10:50
• dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/293860
• dc.relation.projectID info:eu-repo/grantAgreement/ES/3PN/BFU2011-24397
• dc.rights © 2015 González et al. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.ca
• dc.rights.accessRights info:eu-repo/semantics/openAccessca
• dc.rights.uri http://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword Transposable elements
• dc.subject.keyword Evolution Canyon
• dc.subject.keyword Adaptation
• dc.subject.keyword Drosophila melanogaster
• dc.subject.keyword Environmental gradients
• dc.subject.other Adaptació (Biologia)
• dc.title Lack of population differentiation patterns of previously identified putatively adaptive transposable element insertions at microgeographic scalesca
• dc.type info:eu-repo/semantics/articleca
• dc.type.version info:eu-repo/semantics/publishedVersionca