Sex-biased patterns shaped the genetic history of Roma
Mostra el registre complet Registre parcial de l'ítem
- dc.contributor.author García-Fernández, Carla
- dc.contributor.author Font-Porterias, Neus
- dc.contributor.author Kučinskas, Vaidutis
- dc.contributor.author Sukarova-Stefanovska, Emilija
- dc.contributor.author Pamjav, Horolma
- dc.contributor.author Makukh, Halyna
- dc.contributor.author Dobón Berenguer, Begoña, 1987-
- dc.contributor.author Bertranpetit, Jaume, 1952-
- dc.contributor.author Netea, Mihai G
- dc.contributor.author Calafell i Majó, Francesc
- dc.contributor.author Comas, David, 1969-
- dc.date.accessioned 2020-09-22T06:13:25Z
- dc.date.available 2020-09-22T06:13:25Z
- dc.date.issued 2020
- dc.description.abstract The Roma population is a European ethnic minority characterized by recent and multiple dispersals and founder effects. After their origin in South Asia around 1,500 years ago, they migrated West. In Europe, they diverged into ethnolinguistically distinct migrant groups that spread across the continent. Previous genetic studies based on genome-wide data and uniparental markers detected Roma founder events and West-Eurasian gene flow. However, to the best of our knowledge, it has not been assessed whether these demographic processes have equally affected both sexes in the population. The present study uses the largest and most comprehensive dataset of complete mitochondrial and Y chromosome Roma sequences to unravel the sex-biased patterns that have shaped their genetic history. The results show that the Roma maternal genetic pool carries a higher lineage diversity from South Asia, as opposed to a single paternal South Asian lineage. Nonetheless, the European gene flow events mainly occurred through the maternal lineages; however, a signal of this gene flow is also traceable in the paternal lineages. We also detect a higher female migration rate among European Roma groups. Altogether, these results suggest that sociocultural factors influenced the emergence of sex-biased genetic patterns at global and local scales in the Roma population through time.
- dc.format.mimetype application/pdf
- dc.identifier.citation García-Fernández C, Font-Porterias N, Kučinskas V, Sukarova-Stefanovska E, Pamjav H, Makukh H, Dobon B, Bertranpetit J, Netea MG, Calafell F, Comas D. Sex-biased patterns shaped the genetic history of Roma. Sci Rep. 2020; 10(1):14464. DOI: 10.1038/s41598-020-71066-y
- dc.identifier.doi http://dx.doi.org/10.1038/s41598-020-71066-y
- dc.identifier.issn 2045-2322
- dc.identifier.uri http://hdl.handle.net/10230/45319
- dc.language.iso eng
- dc.publisher Nature Research
- dc.relation.ispartof Sci Rep. 2020; 10(1):14464
- dc.rights © The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by/4.0/
- dc.subject.keyword Genetic variation
- dc.title Sex-biased patterns shaped the genetic history of Roma
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion