MAMI: a birth cohort focused on maternal-infant microbiota during early life

García Mantrana, Izaskun; Alcántara, Cristina; Selma Royo, Marta; Boix Amorós, Alba; Dzidic, Majda; Gimeno Alcañiz, Jose; Úbeda Sansano, Isabel; Sorribes Monrabal, Ignacio; Escuriet Peiró, Ramón, 1968-; Gil Raga, Fernando; Parra Llorca, Anna; Martínez Costa, Cecilia; Collado, María Carmen; MAMI team

doi:http://dx.doi.org/10.1186/s12887-019-1502-y

MAMI: a birth cohort focused on maternal-infant microbiota during early life

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García-Mantrana I, Alcántara C, Selma-Royo M, Boix-Amorós A, Dzidic M, Gimeno-Alcañiz J et al. MAMI: a birth cohort focused on maternal-infant microbiota during early life. BMC Pediatr. 2019;19(1):140. DOI: 10.1186/s12887-019-1502-y

Abstract

Early microbial colonization is a relevant aspect in human health. Altered microbial colonization patterns have been linked to an increased risk of non-communicable diseases (NCDs). Advances in understanding host-microbe interactions highlight the pivotal role of maternal microbiota on infant health programming. This birth cohort is aimed to characterize the maternal microbes transferred to neonates during the first 1000 days of life, as well as to identify the potential host and environmental factors, such as gestational age, mode of delivery, maternal/infant diet, and exposure to antibiotics, which affect early microbial colonization.