Prevalence of cardiovascular risk factors in people with epilepsy
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- dc.contributor.author Vivanco Hidalgo, Rosa Maríaca
- dc.contributor.author Gomez, Alejandraca
- dc.contributor.author Moreira Villanueva, Antíaca
- dc.contributor.author Díez, Lauraca
- dc.contributor.author Elosua Llanos, Robertoca
- dc.contributor.author Roquer, Jaumeca
- dc.date.accessioned 2017-11-27T08:41:52Z
- dc.date.available 2017-11-27T08:41:52Z
- dc.date.issued 2016
- dc.description.abstract OBJECTIVES: Epilepsy has been associated with cardiovascular comorbidity. This study aimed to assess the potential association between cardiovascular risk factors (CRFs), antiepileptic drugs (AEDs), and etiology. MATERIAL AND METHODS: A single-center retrospective epilepsy cohort from the decade of 2004-2013 was assessed. Poisson regression models with robust variance were estimated to obtain CRF prevalence ratios (PR) according to AED prescription and etiology. RESULTS: After excluding patients in the monotherapy group with vascular etiology or previous cardiovascular events, in the remaining 400 patients, enzyme-inducer AEDs (EIAEDs), especially phenytoin (PHT), were associated with higher prevalence of dyslipidemia (PRa 1.77, p < .05), compared to valproic acid. No etiology was associated with higher prevalence of any CRF. CONCLUSIONS: Patients treated with EIAEDs, especially PHT, had higher prevalence of dyslipidemia.
- dc.format.mimetype application/pdfca
- dc.identifier.citation Vivanco-Hidalgo RM, Gomez A, Moreira A, Díez L, Elosua R, Roquer J. Prevalence of cardiovascular risk factors in people with epilepsy. Brain Behav. 2016 Dec 20;7(2):e00618. DOI: 10.1002/brb3.618
- dc.identifier.doi http://dx.doi.org/10.1002/brb3.618
- dc.identifier.issn 2162-3279
- dc.identifier.uri http://hdl.handle.net/10230/33337
- dc.language.iso eng
- dc.publisher Wileyca
- dc.relation.ispartof Brain and Behavior. 2016 Dec 20;7(2):e00618
- dc.rights Copyright © 2016 The Authors. Brain and Behavior published by Wiley Periodicals, Inc. This is an open access article under the terms of the https://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.subject.keyword Antiepileptic drugs
- dc.subject.keyword Cardiovascular risk factors
- dc.subject.keyword Comorbidity
- dc.subject.keyword Epilepsy
- dc.subject.other Epilèpsia
- dc.subject.other Cor -- Malalties
- dc.title Prevalence of cardiovascular risk factors in people with epilepsyca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/acceptedVersion