Imatinib treatment of lymphomatoid papulosis associated with myeloproliferative hypereosinophilic syndrome presenting the FIP1L1-PDGFRA fusion gene.
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- dc.contributor.author García-Martínez, Pabloca
- dc.contributor.author Sitjas, Dolorsca
- dc.contributor.author Llistosella, Enricca
- dc.contributor.author Espinet Solà, Blancaca
- dc.contributor.author Rodríoguez Rivera, Maríaca
- dc.contributor.author Gallardo Hernández, Fernandoca
- dc.contributor.author Pujol Vallverdú, Ramon Mariaca
- dc.date.accessioned 2017-11-07T11:49:25Z
- dc.date.available 2017-11-07T11:49:25Z
- dc.date.issued 2017
- dc.description.abstract Peripheral blood eosinophilia has been reported to occur in a wide range of haematological malignancies including primary cutaneous lymphomas. The concurrence of lymphomatoid papulosis (LyP) with peripheral blood eosinophilia seems to be an uncommon phenomenon. Atypical lymphocytes in LyP display the phenotype of activated T-helper cells, consistently express CD30 antigen, have a Th2 cytokine profile, and secrete eosinophilstimulating cytokines. Cases of LyP have been reported in association with myeloproliferative hypereosinophilic syndrome (M-HES) presenting the Fip1-like 1/plateletderived growth factor receptor-α (FIP1L1-PDGFRA) fusion gene. In such cases, imatinib treatment may lead to a complete and persistent resolution of LyP lesions.
- dc.format.mimetype application/pdfca
- dc.identifier.citation García-Martínez P, Sitjas D, Llistosella E, Espinet B, Rodríguez-Rivera M, Hernandez-Muñoz M. Imatinib treatment of lymphomatoid papulosis associated with myeloproliferative hypereosinophilic syndrome presenting the FIP1L1-PDGFRA fusion gene. Acta Derm Venereol. 2017 Jul 6;97(7):855-857. DOI: 10.2340/00015555-2669
- dc.identifier.doi http://dx.doi.org/10.2340/00015555-2669
- dc.identifier.issn 0001-5555
- dc.identifier.uri http://hdl.handle.net/10230/33163
- dc.language.iso eng
- dc.publisher Society for Publication of Acta Dermato-Venereologicaca
- dc.relation.ispartof Acta Dermato-Venereologica. 2017 Jul 6;97(7):855-7
- dc.rights This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta Journal Compilation © 2017 Acta Dermato-Venereologica.
- dc.rights.accessRights info:eu-repo/semantics/openAccess
- dc.rights.uri http://creativecommons.org/licenses/by-nc/4.0/
- dc.subject.other Limfomes -- Tractament
- dc.title Imatinib treatment of lymphomatoid papulosis associated with myeloproliferative hypereosinophilic syndrome presenting the FIP1L1-PDGFRA fusion gene.ca
- dc.type info:eu-repo/semantics/article
- dc.type.version info:eu-repo/semantics/publishedVersion