Cardio-pulmonary dysfunction evaluation in patients with persistent post-COVID-19 headache

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• dc.contributor.author Aparisi, Álvaro
• dc.contributor.author Ybarra-Falcón, Cristina
• dc.contributor.author Iglesias-Echeverría, Carolina
• dc.contributor.author García-Gómez, Mario
• dc.contributor.author Marcos-Mangas, Marta
• dc.contributor.author Valle-Peñacoba, Gonzalo
• dc.contributor.author Carrasco-Moraleja, Manuel
• dc.contributor.author Fernández-de-Las-Peñas, César
• dc.contributor.author Guerrero, Ángel L.
• dc.contributor.author García-Azorín, David
• dc.date.accessioned 2022-09-22T07:02:00Z
• dc.date.available 2022-09-22T07:02:00Z
• dc.date.issued 2022
• dc.description.abstract Background (1): Headache is a prevalent symptom experienced during ongoing SARS-CoV-2 infection, but also weeks after recovery. Whether cardio-pulmonary dysfunction contributes causally to headache persistence is unknown. Methods (2): We conducted a case-control analysis nested in a prospective cohort study. Individuals were recruited from August 2020 to December 2020. Patients were grouped according to the presence or absence of long-COVID headache for three months after COVID-19 resolution. We compared demographic data, clinical variables, cardio-pulmonary laboratory biomarkers, quality of life, and cardio-pulmonary function between groups. Results (3): A cohort of 70 COVID-19 patients was evaluated. Patients with headaches (n = 10; 14.3%) were more frequently female (100% vs. 58.4%; p = 0.011) and younger (46.9 ± 8.45 vs. 56.13 ± 12 years; p = 0.023). No between-group differences in laboratory analysis, resting echocardiography, cardio-pulmonary exercise test, or pulmonary function tests were observed. Conclusion (4): In this exploratory study, no significant differences in cardio-pulmonary dysfunction were observed between patients with and without long-COVID headache during mid-term follow-up.
• dc.format.mimetype application/pdf
• dc.identifier.citation Aparisi Á, Ybarra-Falcón C, Iglesias-Echeverría C, García-Gómez M, Marcos-Mangas M, Valle-Peñacoba G, Carrasco-Moraleja M, Fernández-de-Las-Peñas C, Guerrero ÁL, García-Azorín D. Cardio-pulmonary dysfunction evaluation in patients with persistent post-COVID-19 headache. Int J Environ Res Public Health. 2022 Mar 26;19(7):3961. DOI: 10.3390/ijerph19073961
• dc.identifier.doi http://dx.doi.org/10.3390/ijerph19073961
• dc.identifier.issn 1661-7827
• dc.identifier.uri http://hdl.handle.net/10230/54148
• dc.language.iso eng
• dc.publisher MDPI
• dc.relation.ispartof Int J Environ Res Public Health. 2022 Mar 26;19(7):3961
• dc.rights © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
• dc.rights.accessRights info:eu-repo/semantics/openAccess
• dc.rights.uri https://creativecommons.org/licenses/by/4.0/
• dc.subject.keyword COVID-19
• dc.subject.keyword Cardio-pulmonary exercise testing
• dc.subject.keyword Headache disorders
• dc.subject.keyword Long-COVID syndrome
• dc.title Cardio-pulmonary dysfunction evaluation in patients with persistent post-COVID-19 headache
• dc.type info:eu-repo/semantics/article
• dc.type.version info:eu-repo/semantics/publishedVersion