The genomic basis of evolutionary differentiation among honey bees

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  • dc.contributor.author Fouks, Bertrand
  • dc.contributor.author Camara, Francisco
  • dc.contributor.author Guigó Serra, Roderic
  • dc.contributor.author Rueppell, Olav
  • dc.date.accessioned 2021-11-22T07:50:15Z
  • dc.date.available 2021-11-22T07:50:15Z
  • dc.date.issued 2021
  • dc.description.abstract In contrast to the western honey bee, Apis mellifera, other honey bee species have been largely neglected despite their importance and diversity. The genetic basis of the evolutionary diversification of honey bees remains largely unknown. Here, we provide a genome-wide comparison of three honey bee species, each representing one of the three subgenera of honey bees, namely the dwarf (Apis florea), giant (A. dorsata), and cavity-nesting (A. mellifera) honey bees with bumblebees as an outgroup. Our analyses resolve the phylogeny of honey bees with the dwarf honey bees diverging first. We find that evolution of increased eusocial complexity in Apis proceeds via increases in the complexity of gene regulation, which is in agreement with previous studies. However, this process seems to be related to pathways other than transcriptional control. Positive selection patterns across Apis reveal a trade-off between maintaining genome stability and generating genetic diversity, with a rapidly evolving piRNA pathway leading to genomes depleted of transposable elements, and a rapidly evolving DNA repair pathway associated with high recombination rates in all Apis species. Diversification within Apis is accompanied by positive selection in several genes whose putative functions present candidate mechanisms for lineage-specific adaptations, such as migration, immunity, and nesting behavior.
  • dc.format.mimetype application/pdf
  • dc.identifier.citation Fouks B, Brand P, Nguyen HN, Herman J, Camara F, Ence D et al. The genomic basis of evolutionary differentiation among honey bees. Genome Res. 2021;31(7):1203-15. DOI: 10.1101/gr.272310.120
  • dc.identifier.doi http://dx.doi.org/10.1101/gr.272310.120
  • dc.identifier.issn 1088-9051
  • dc.identifier.uri http://hdl.handle.net/10230/49032
  • dc.language.iso eng
  • dc.publisher Cold Spring Harbor Laboratory Press (CSHL Press)
  • dc.relation.ispartof Genome Res. 2021;31(7):1203-15
  • dc.rights © 2021 Fouks et al.; Published by Cold Spring Harbor Laboratory Press. This article, published in Genome Research, is available under a Creative Commons License (Attribution 4.0 International), as described at http://creativecommons.org/licenses/by/4.0/.
  • dc.rights.accessRights info:eu-repo/semantics/openAccess
  • dc.rights.uri http://creativecommons.org/licenses/by/4.0/
  • dc.title The genomic basis of evolutionary differentiation among honey bees
  • dc.type info:eu-repo/semantics/article
  • dc.type.version info:eu-repo/semantics/publishedVersion

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Articles (Center for Genomic Regulation (CRG))